Cardiology pp 517-523 | Cite as

Limitation of Infarct Size: Theoretical Aspects

  • G. Baroldi

Abstract

The basic postulate is that cardiac infarct size is directly related to clinical complications and death. The consequent therapeutical implication is to reduce the “theoretical” size and/or to prevent its progression (or expansion) in the surrounding myocardium. The latter is considered more prone to is chaemia and therefore at high risk of necrosis (“jeopardized border zone”).

Keywords

Infarct Size Myocardial Cell Myocardial Fibrosis Myocardial Necrosis Normal Myocardium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    G. Baroldi, F. Radice, C. Schmid and A. Leone, Morphology of acute myocardial infarction in relation to coronary thrombosis. Am. Heart J., 87:65 (1974).PubMedCrossRefGoogle Scholar
  2. 2.
    M. D. Silver, G. Baroldi and F. Mariani, The relationship between acute occlusive coronary thrombi and myocardial infarction studies in 100 consecutive patients. Circulation, 61:219 (1980).PubMedCrossRefGoogle Scholar
  3. 3.
    G. Baroldi, Different types of myocardial necrosis in coronary heart disease: a pathophysiological review of their functional significance. Am. Heart J., 89:742 (1975).PubMedCrossRefGoogle Scholar
  4. 4.
    G. Baroldi, G. Falzi and F. Mariani, Sudden coronary death. A postmortem study in 208 selected cases compared to 97 “control” subjects. Am. Heart J., 98:20 (1979).PubMedCrossRefGoogle Scholar
  5. 5.
    G. Baroldi, Pathology and Mechanisms of Sudden Death, in “The Heart” J. W. Hurst ed., McGraw-Hill Book Co., New York, 5th Edition, p. 393 (1982).Google Scholar
  6. 6.
    G. Baroldi, M. D. Silver, W. Lixfeld and D. C. McGregor, Irreversible myocardial damage resembling catecholamine necrosis secondary to acute coronary occlusion in dogs: its prevention by propranolol. J. Molec. Cell. Cardiol., 9:687 (1977).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • G. Baroldi
    • 1
    • 2
  1. 1.Institute of Clinical Physiology, C. N. R.University of PisaItaly
  2. 2.Institute of Pathological Anatomy, Medical SchoolUniversity of MilanItaly

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