Cardiology pp 327-336 | Cite as

Alteration of Cell Membranes in Primary Hypertension

  • Yu. V. Postnov
  • S. N. Orlov

Abstract

The past few years have witnessed a rapid accumulation of facts which give reason to believe that primary hypertension (essential hypertension in humans as well as spontaneous hypertension in KyotoWistar rats) is causally associated to a wide-spread alteration of the cell membrane’s regulation of intracellular free calcium and transport of univalent cations. In 1975–1978 we suggested that the hypertensive syndrome in primary hypertension is the manifestation of a certain type of membrane pathology19–21. Within a short period of time this hypothesis gradually began to gain ground. Below we present our data.

Keywords

Essential Hypertension Erythrocyte Membrane Primary Hypertension Free Calcium Concentration Spontaneous Hypertension 
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • Yu. V. Postnov
    • 1
  • S. N. Orlov
    • 1
  1. 1.USSR Ministry of Public HealthCentral Research LaboratoryMoscowUSSR

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