Alteration of Cell Membranes in Primary Hypertension
The past few years have witnessed a rapid accumulation of facts which give reason to believe that primary hypertension (essential hypertension in humans as well as spontaneous hypertension in KyotoWistar rats) is causally associated to a wide-spread alteration of the cell membrane’s regulation of intracellular free calcium and transport of univalent cations. In 1975–1978 we suggested that the hypertensive syndrome in primary hypertension is the manifestation of a certain type of membrane pathology19–21. Within a short period of time this hypothesis gradually began to gain ground. Below we present our data.
KeywordsEssential Hypertension Erythrocyte Membrane Primary Hypertension Free Calcium Concentration Spontaneous Hypertension
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