Reactions of Carbon Nucleophiles with Carbonyl Groups

  • Francis A. Carey
  • Richard J. Sundberg
Part of the Advanced Organic Chemistry book series

Abstract

The reactions described in this chapter include some of the most useful and frequently employed synthetic methods for carbon—carbon bond formation: aldol and Claisen condensation reactions,the Wittig and related olefination reactions, and the Robinson annulation. All of these processes involve, at some point, the addition of a carbon nucleophile to a carbonyl group. The type of product which is isolated depends on the nature of the substituent (X) on the carbon nucleophile, the substituents (A and B) on the carbonyl group, and the ways in which A, B, and X affect the reaction pathways available to the intermediate formed in the addition step.

Keywords

Carbonyl Compound Aldol Condensation Mannich Reaction Phosphonium Salt Wittig Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Francis A. Carey
    • 1
  • Richard J. Sundberg
    • 1
  1. 1.University of VirginiaCharlottesvilleUSA

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