Benign Lesions of the Cervix

  • Alex Ferenczy


Acute inflammation of the cervix results from direct infection by nonspecific microorganisms or by secondary invaders. The former group includes streptococci, staphylococci, and enterococci, and infections with these organisms are prone to occur in puerperal infections. Among the most common secondary invaders are the gram-negative diplococci, Neisseria gonorrhoea, Trichomonas vaginalis, and Candida albicans. Foreign bodies introduced into the vagina, namely, fragments of residual tampons and pesseries, may also lead to acute cervical inflammation. Clinically, acute cervicitis is manifested by purulent, malodorous vaginal discharge, which is yellowish green when the infection is caused by Trichomonas and whitish, colorless with white flakes when Candida is the causative agent. Backache, vulvar pruritus, and painful urination, when the urethra is involved, are often accompanied by vaginal discharge.


Obstet Gynecol Cervix Uterus Verrucous Carcinoma Condyloma Acuminata Squamocolumnar Junction 
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  1. 1.
    Aaro LA, Jacobson LJ, Soule EH (1963) Endocervi-cal polyps. Obstet Gynecol 21: 659PubMedGoogle Scholar
  2. 2.
    Abell MR (1971) Papillary adenofibroma of the uterine cervix. Am J Obstet Gynecol 110: 990PubMedGoogle Scholar
  3. 3.
    Abell MR, Gosling JRG (1962) Gland cell carcinoma (adenocarcinoma) of the uterine cervix. Am J Obstet Gynecol 83: 729PubMedGoogle Scholar
  4. 4.
    Adam E, Kaufman RH, Melnick JL, Levy AH, Rawls WE (1972) Seroepidemiologic studies of herpesvirus type 2 and carcinoma of the cervix. III. Houston, Texas, Am J Epidemiol 96: 427PubMedGoogle Scholar
  5. 5.
    Adam E, Kaufman RH, Melnick JL, Levy AH, Rawls WE (1973) Seroepidemiologic studies of herpesvirus type 2 and carcinoma of the cervix. IV. Dysplasia and carcinoma in situ. Am J Epidemiol 98: 77PubMedGoogle Scholar
  6. 6.
    Adams JQ, Packer H (1955) Granuloma inguinale of the cervix. South Med J 48: 27PubMedCrossRefGoogle Scholar
  7. 7.
    Berry A (1966) A cytopathological and histopatho-logical study of bilharziasis of the female genital tract. J Pathol Bacteriol 91: 325PubMedCrossRefGoogle Scholar
  8. 8.
    Burd LI, Esterly JR (1971) Vesicular lesions of the uterine cervix. Am J Obstet Gynecol 110: 887PubMedGoogle Scholar
  9. 9.
    Busby JG (1952) Neurofibromatosis of the cervix. Am J Obstet Gynecol 63: 674PubMedGoogle Scholar
  10. 10.
    Candy J, Abell MR (1968) Progestogen-induced adenomatous hyperplasia of the uterine cervix. JAMA 203: 323CrossRefGoogle Scholar
  11. 11.
    Chang SH, Maddox WA (1971) Adenocarcinoma arising within cervical endometriosis and invading the adjacent vagina. Am J Obstet Gynecol 110: 1015PubMedGoogle Scholar
  12. 12.
    Clement PB, Scully, RE (1974) Müllerian adeno-sarcoma of the uterus. Cancer 34: 1138PubMedCrossRefGoogle Scholar
  13. 13.
    Cohen C (1973) Three cases of amoebiasis of the cervix uteri. J Obstet Gynaecol Br Commonw 80: 476PubMedCrossRefGoogle Scholar
  14. 14.
    Crossen RJ (1930) A case of gumma of cervix. Am J Obstet Gynecol 19: 708Google Scholar
  15. 15.
    Crow J, McWhinney N (1979) Isolated arteritis of the cervix uteri. Br J Obstet Gynecol 86: 393CrossRefGoogle Scholar
  16. 16.
    De Molnar AMD, Guralnick M, Ferenczy A (1978) Blue nevus of the endocervix: Report of two cases and ultrastructure. Gynecol Oncol 6: 373CrossRefGoogle Scholar
  17. 17.
    Dougherty CM, Moore WR, Cotten N (1962) Histologic diagnosis and clinical significance of benign lesions of the nonpregnant cervix. Ann NY Acad Sci 97: 683CrossRefGoogle Scholar
  18. 18.
    Dun AEG, Ogilvie MM (1968) Intranuclear virus particles in human genital wart tissue: Observation on the ultrastructure of the epidermal layer. J Ultrastruct Res 22: 282PubMedCrossRefGoogle Scholar
  19. 19.
    Elliott GB, Elliott JDA (1973) Superficial stromal reactions of lower genital tract. Arch Pathol 95: 100PubMedGoogle Scholar
  20. 20.
    Elliott GB, Reynolds HA, Fidler HK (1967) Pseu-dosarcoma botryoides of cervix and vagina in pregnancy. J Obstet Gynaecol Br Commonw 74: 728PubMedCrossRefGoogle Scholar
  21. 21.
    El-Mahgoub S (1972) Antispermatozoal antibodies in infertile women with cervicovaginal schistosomiasis. Am J Obstet Gynecol 112: 781PubMedGoogle Scholar
  22. 22.
    Fingerland A, Sikl H (1938) Ganglioneuroma of cervix uteri. J Pathol Bacterol 47: 631CrossRefGoogle Scholar
  23. 23.
    Fluhman CF (1961) The cervix uteri and its diseases, 1st ed. Philadelphia, WB SaundersGoogle Scholar
  24. 24.
    Gardner HL (1966) Cervical and vaginal endometriosis. Clin Obstet Gynecol 9: 358PubMedCrossRefGoogle Scholar
  25. 25.
    Gardner HL, Fernet P (1964) Etiology of vaginitis emphysematosa. Am J Obstet Gynecol 88: 680PubMedGoogle Scholar
  26. 26.
    Grimait M, Argueles M, Ferenczy A (1975) Papillary cystadenofibroma of endometrium. A histochemical and ultrastructural study. Cancer 36: 137CrossRefGoogle Scholar
  27. 27.
    Gusdon JT (1965) Hemangioma of the cervix. Am J Obstet Gynecol 91: 204PubMedGoogle Scholar
  28. 28.
    Janovski MS Kasdon EJ (1963) Benign meso-nephric papillary and polypoid tumors of the cervix in childhood. J Pediatr 63: 211PubMedCrossRefGoogle Scholar
  29. 29.
    Kaufman RH, Gardner HL, Rawls WE, Dixon RE, Young RL (1973) Clinical features of herpes genitalis. Cancer Res 33: 1446PubMedGoogle Scholar
  30. 30.
    Kaufman RH, Watts JM, Gardner HL (1969) Pemphigus vulgaris genital involvement. Obstet Gynecol 33: 264PubMedGoogle Scholar
  31. 31.
    Kistner RW, Hertig AT (1955) Papillomas of the uterine cervix—Their malignant potentiality. Obstet Gynecol 6: 147PubMedGoogle Scholar
  32. 32.
    Koss LG, Wolinska WH (1959) Trichomonas vaginalis cervicitis and its relationship to cervical cancer; a histocytological study. Cancer 12: 1171PubMedCrossRefGoogle Scholar
  33. 33.
    Langley GF (1943) Primary echinococcal cyst of the uterus. Br J Surg 30: 278CrossRefGoogle Scholar
  34. 34.
    Laverty CR, Booth N, Hills E, Cossart Y, Wills EJ (1978) Noncondylomatous wart virus infection of the postmenopausal cervix. Pathology 10: 373–378PubMedCrossRefGoogle Scholar
  35. 35.
    Laverty CR, Russel P, Hills E, Booth N (1978) The significance of noncondylomatous wart virus infection of the cervical transformation zone. A review with discussion of two illustrative cases. Acta Cytol 22: 195–201PubMedGoogle Scholar
  36. 36.
    Lippert LJ, Richart RM, Ferenczy A (1974) Giant benign endocervical polyp: Report of a case. Am J Obstet Gynecol 118: 1140PubMedGoogle Scholar
  37. 37.
    Lucas WE, Benirschke K, Lebherz TB (1974) Verrucous carcinoma of the female genital tract. Am J Obstet Gynecol 119: 435PubMedGoogle Scholar
  38. 38.
    Meisels A, Roy M, Fortier M, Morin C (1979) Con-dylomatous lesions of the cervix. Morphologic and colposcopy diagnosis. Am J Diagn Gynecol Obstet 1: 109Google Scholar
  39. 39.
    Nahmias AJ, Roizman B (1973) Infection with Herpes-simplex viruses 1 and 2. N Engl J Med 289: 667, 719, 781CrossRefGoogle Scholar
  40. 40.
    Newton WL, Reardon LV, DeLeva AM (1960) A comparative study of the subcutaneous innoculation of germ free and conventional guinea pigs with two strains of Trichomonas vaginalis.Am J Trop Med Hyg 9: 56PubMedGoogle Scholar
  41. 41.
    Nichols TM, Fidler HK (1971) Microglandular hyperplasia in cervical cone biopsies taken for suspicious and positive cytology. Am J Clin Pathol 56: 424PubMedGoogle Scholar
  42. 42.
    Norris HJ, Taylor HB (1966) Polyps of the vagina: A benign lesion resembling sarcoma botryoides. Cancer 19: 226Google Scholar
  43. 43.
    Richart RM (1973) Cervical intraepithelial neoplasia. In: Pathology annual, Sommers SC (ed). New York, Appleton-Century-Crofts, pp 301–328Google Scholar
  44. 44.
    Richter GA, Pratt JH, Nichols DR, Coulam CB (1972) Actinomycosis of the female genital organs. Minn Med 55: 1003PubMedGoogle Scholar
  45. 45.
    Ridley JH (1968) The histogenesis of endometriosis. A review of facts and fancies. Obstet Gynecol Surv 23: 1CrossRefGoogle Scholar
  46. 46.
    Rilke F, Cantaboni A (1964) Lipomas of the uterus. Presentation of 2 cases and review of the recent literature. Ann Obstet Gynecol 86: 645Google Scholar
  47. 47.
    Robboy SJ, Welch WR (1977) Microglandular hyperplasia in vaginal adenosis associated with oral contraceptives and prenatal diethylstilbestrol exposure. Obstet Gynecol 49: 430PubMedGoogle Scholar
  48. 48.
    Schaefer C (1970) Tuberculosis of female genital tract. Clin Obstet Gynecol 13: 965PubMedCrossRefGoogle Scholar
  49. 49.
    Schacter J (1978) Chlamydial infections. N Engl J Med 298: 428, 490, 540CrossRefGoogle Scholar
  50. 50.
    Selzer F, Nelson HM (1962) Benign papilloma (polypoid tumor) of the cervix uteri in children; report of two cases. Am J Obstet Gynecol 84: 165PubMedGoogle Scholar
  51. 51.
    Slavutin L (1979) Uterine Gliosis and ossification. Am J Diagn Gynecol Obstet 1: 351Google Scholar
  52. 52.
    Stein BJ, Siciliano A (1966) Necrotizing Herpes simplex viral infection of the cervix during pregnancy: Mimic of squamous cell carcinoma. Am J Obstet Gynecol 94: 249PubMedGoogle Scholar
  53. 53.
    Stout AP (1943) Hemangio-endothelioma: A tumor of blood vessels featuring vascular endothelial cells. Ann Surg 118: 445PubMedCrossRefGoogle Scholar
  54. 54.
    Taylor HB, Irey NS, Norris HJ (1967) Atypical en-docervical hyperplasia in women taking oral contraceptives. JAMA 202: 637PubMedCrossRefGoogle Scholar
  55. 55.
    Tchertkoff V, Ober WB (1966) Primary chancre of the cervix uteri NY State J Med 66: 1921Google Scholar
  56. 56.
    Vellios F, Ng ABP, Reagan JW (1973) Papillary adenofibroma of the uterus. A benign mesodermal mixed tumor of Miillerian origin. Am J Clin Pathol 60: 543PubMedGoogle Scholar
  57. 57.
    Wagner EK (1974) The replication of herpesvirus. Am Sci 62: 584Google Scholar
  58. 58.
    Wilbanks GD, Carter B (1963) Vaginitis emphysematosa. Obstet Gynecol 22: 301PubMedGoogle Scholar

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© Springer Science+Business Media New York 1982

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  • Alex Ferenczy

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