Gestational Trophoblast Disease

  • Bradley Bigelow


The somewhat awkward title of this chapter on placental pathology is a reflection of the age-old difficulty in understanding the pathogenesis and predicting the behavior of a very fascinating group of gestational abnormalities. Three conditions are included: hydatidiform mole, invasive mole (chorioadenoma destruens), and choriocarcinoma. They run the gamut from degenerative to neoplastic processes. Although connecting links between them are demonstrable, both in clinical situations and in the laboratory, the unpredictability persists despite years of observation and analysis.


Obstet Gynecol Normal Pregnancy Hydatidiform Mole Gestational Trophoblast Disease Molar Pregnancy 
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© Springer Science+Business Media New York 1982

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  • Bradley Bigelow

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