Transduction is the term used to designate the bacteriophage-mediated transfer of DNA from one cell (a donor) to another cell (a recipient). It was first described by Zinder and Lederberg for Salmonella and phage P22 but has since been shown to occur in many other bacteria and to involve a variety of bacteriophages. Depending upon which virus is involved, the donor cell DNA may or may not be associated with viral DNA inside the capsid of the bacteriophage. However, in all cases of transduction it is necessary for the donor cell to lyse and for the virions carrying host DNA (the transducing particles) to be capable of injecting their DNA into a new cell. A cell which has acquired a recombinant phenotype due to this process is called a transductant.
KeywordsBacterial Genome Bacteriophage Lambda Generalize Transduce Helper Phage Specialized Transduce
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- Campbell, A. 1977. Defective bacteriophages and incomplete prophages, pp. 259–328. In: Fraenkel-Conrat, H., Wagner, R.R. (eds.) Comprehensive Virology, vol. 8. New York: Plenum Press.Google Scholar
- Franklin, N.C. 1971. Illegitimate recombination, pp. 175–194. In: Hershey, A.D. (ed.) The Bacteriophage Lambda. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory.Google Scholar
- Echols, H., Court, D. 1971. The role of helper phage in gal transduction, pp. 701–710. In: Hershey, A.D. (ed.) The Bacteriophage Lambda. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory.Google Scholar