Skip to main content

Transduction

  • Chapter
  • 147 Accesses

Part of the book series: Springer Series in Microbiology ((SSMIC))

Abstract

Transduction is the term used to designate the bacteriophage-mediated transfer of DNA from one cell (a donor) to another cell (a recipient). It was first described by Zinder and Lederberg for Salmonella and phage P22 but has since been shown to occur in many other bacteria and to involve a variety of bacteriophages. Depending upon which virus is involved, the donor cell DNA may or may not be associated with viral DNA inside the capsid of the bacteriophage. However, in all cases of transduction it is necessary for the donor cell to lyse and for the virions carrying host DNA (the transducing particles) to be capable of injecting their DNA into a new cell. A cell which has acquired a recombinant phenotype due to this process is called a transductant.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   74.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

General

  • Campbell, A. 1977. Defective bacteriophages and incomplete prophages, pp. 259–328. In: Fraenkel-Conrat, H., Wagner, R.R. (eds.) Comprehensive Virology, vol. 8. New York: Plenum Press.

    Google Scholar 

  • Franklin, N.C. 1971. Illegitimate recombination, pp. 175–194. In: Hershey, A.D. (ed.) The Bacteriophage Lambda. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory.

    Google Scholar 

  • Sik, T., Horváth, J., Chatterjee, S. 1980. Generalized transduction in Rhizobium meliloti. Molecular and General Genetics. 178:511–516.

    Article  PubMed  CAS  Google Scholar 

  • Susskind, M.M., Botstein, D. 1978. Molecular genetics of bacteriophage P22. Microbiological Reviews 42:385–413.

    PubMed  CAS  Google Scholar 

Specialized

  • Borchert, L.D., Drexler, H. 1980. T1 genes which affect transduction. Journal of Virology 33:1122–1128.

    PubMed  CAS  Google Scholar 

  • Chesney, R.H., Scott, J.R., Vapnek, D. 1979. Integration of the plasmid prophages P1 and P7 into the chromosome of E. coli. Journal of Molecular Biology 130:161–173.

    Article  PubMed  CAS  Google Scholar 

  • Ebel-Tsipis, J., Botstein, D., Fox, M.S. 1972. Generalized transduction by phage P22 in S. typhimurium. I. Molecular origin of transducing DNA. Journal of Molecular Biology 71:433–448.

    Article  PubMed  CAS  Google Scholar 

  • Ebel-Tsipis, J., Fox, M.S., Botstein, D. 1972. Generalized transduction by bacteriophage P22 in S. typhimurium. II. Mechanism of integration of transducing DNA. Journal of Molecular Biology 71:449–469.

    Article  PubMed  CAS  Google Scholar 

  • Echols, H., Court, D. 1971. The role of helper phage in gal transduction, pp. 701–710. In: Hershey, A.D. (ed.) The Bacteriophage Lambda. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory.

    Google Scholar 

  • Faelen, M., Toussaint, A., Resibois, A. 1979. Mini-Muduction—new mode of gene transfer mediated by mini-Mu. Molecular and General Genetics 176:191–197.

    PubMed  CAS  Google Scholar 

  • Gottesman, S., Beckwith, J.R. 1969. Directed transposition of the arabinose operon: a technique for the isolation of specialized transducing bacteriophages for any E. coli gene. Journal of Molecular Biology 44:117–127.

    Article  PubMed  CAS  Google Scholar 

  • Krajewska-Grynkiewicz, K., Kłopotowski, T. 1979. Altered linkage values in phage P22 mediated transduction caused by distant deletions or insertions in donor chromosomes. Molecular and General Genetics 176:87–93.

    Article  PubMed  CAS  Google Scholar 

  • Shimada, K., Weisberg, R.A., Gottesman, M.E. 1972. Prophage lambda at unusual chromosomal locations I. Location of the secondary attachment sites and the properties of the lysogens. Journal of Molecular Biology 63:483–503.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1981 Springer Science+Business Media New York

About this chapter

Cite this chapter

Birge, E.A. (1981). Transduction. In: Bacterial and Bacteriophage Genetics. Springer Series in Microbiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-1749-5_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-1749-5_7

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-1751-8

  • Online ISBN: 978-1-4757-1749-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics