Abstract
The concept of manipulating phenotypic traits has been known to mankind for a longer period of time than the science of genetics itself. Selective breeding of plants and animals has been practiced for hundreds of years and has resulted in hardier forms of domestic animals and plants as well as such oddities as the various breeds of dogs. With the advent of the science of genetics, interest in this type of activity increased and broadened to include both the possibility of correcting “inborn errors of metabolism” and the possibility of a definitive eugenics program (the application of selective breeding principles to man).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
General
Abelson, J. 1980. A revolution in biology. Science 209:1319–1321.
Ehrlich, S.D. 1978. Bacillus subtilis and the cloning of DNA. Trends in Biochemical Sciences 3:184–186.
Ehrlich, S.D., Sgaramella, V. 1978. Barriers to the heterospecific gene expression among prokaryotes. Trends in Biochemical Sciences 3:259–261.
Gilbert, W., Villa-Komaroff, L. 1980. Useful proteins from recombinant bacteria. Scientific American 242(4):74–94.
Helinski, D. R. 1978. Plasmids as vehicles for gene cloning: impact on basic and applied research. Trends in Biochemical Sciences 3:10–14.
Jackson, D.A., Stich, S.P. (eds.) 1979. The Recombinant DNA Debate. EnglewoodCliffs: Prentice Hall.
Levy, S.B., Marshall, B., Rowse-Eagle, D., Onderdonk, A. 1980. Survival of E. coli host-vector systems in the mammalian intestine. Science 209:391–394.
Nathans, D., Smith, H.O. 1975. Restriction endonucleases in the analysis and restructuring of DNA molecules. Annual Review of Biochemistry 44:273–293.
Research with Recombinant DNA. 1977. An Academy Forum. Washington, D.C.: National Academy of Sciences of the United States of America.
Roberts, R.J. 1980. Restriction and modification enzymes and their recognition sequences. Nucleic Acids Research 8:r6β-r80.
Robeson, J.P., Goldschmidt, R.M., Curtiss III, R., 1980. Potential of E. coli isolated from nature to propagate cloning vectors. Nature 283:104–106
Setlow, J.K., Hollaender, A. (eds.) 1980. Genetic Engineering, Principles and Methods, volume 2. New York: Plenum Press.
Smith, H.O. 1979. Nucleotide sequence specificity of restriction endonucleases. Science 205:455–462.
Specialized
Alwine, J.C., Kemp, D.J., Stark, G.R. 1977. Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes. Proceedings of the National Academy of Sciences of the United States of America 74:5350–5354.
Barrell, B.G., Bankier, A.T., Drouin, J. 1979. A different genetic code in human mitochondria. Nature 282:189–194.
Bibb, M., Schottel, J.L., Cohen, S.N. 1980. A DNA cloning system for interspecies gene transfer in antibiotic-producing Streptomyces. Nature 284:526–531.
Blattner, F.R., Williams, B.G., Blechl, A.E., Denniston-Thompson, K., Faber, H. E., Furlong, L.-A., Grunwald, D.J., Kiefer, D.O., Moore, D.D., Schumm, J.W., Sheldon, E.L., Smithies, O. 1977. Charon phages: safer derivatives of bacteriophage lambda for DNA cloning. Science 196:161–169.
Curtiss, R., III, Pereira, D.A., Hsu, J.C., Hull, S.C., Clark, J.E., Maturin, L.J., Sr., Goldschmidt, R., Moody, R., Inoue, M., Alexander, L. 1977. Biological containment: the subordination of E. coli K-12, pp. 45–56. In: Beers, R.F., Jr., Bassett, E.G. (eds.) Recombinant Molecules: Impact on Science and Society. New York: Raven Press.
Department of Health, Education, and Welfare, National Institutes of Health. 1978. Guidelines for research involving recombinant DNA molecules. Federal Register 45(20):6724–6749.
Goeddel, D.V., Heyneker, H.L., Hozumi, T., Arentzen, R., Itakura, K., Yansura, D.G., Ross, M.J., Miozzari, G., Crea, R., Seeburg, P.H. 1979. Direct expression in E. coli of a DNA sequence coding for human growth hormone. Nature 281:544–548.
Guarente, L., Roberts, T.M., Ptashne, M. 1980. A technique for expressing eukaryotic genes in bacteria. Science 209:1428–1430.
Hardies, S.C., Patient, R.K., Klein, R. D., Ho, F., Reznikoff,W. S., Wells, R.D. 1979. Construction and mapping of recombinant plasmids used for the preparation of DNA fragments containing the E. coli lactose operator and promoter. Journal of Biological Chemistry 254:5527–5534.
Hautala, J.A., Bassett, C.L., Giles, N.H., Kushner, S.R.1979. Increased expression of a eukaryotic gene in E. coli through stabilization of its messenger RNA. Proceedings of the National Academy of Sciences of the United States of America 76:5774–5778.
Herrmann, R., Neugebauer, K., Pirkl, E., Zentgraf, H., Schaller, H. 1980. Conversion of bacteriophage fd into an efficient single-stranded DNA vector system. Molecular and General Genetics 177:231–242.
Horinouchi, S., Uozumi, T., Beppu, T. 1980. Cloning of Streptomyces DNA into E. coli: absence of heterospecific gene expression of Streptomyces genes in E. coli. Agricultural and Biological Chemistry 44:367–381.
Ozaki, L.S., Maeda, S., Shimada, K., Takagi, Y. 1980. A novel ColE1::Tn3 plasmid vector that allows direct selection of hybrid clones in E. coli. Gene 8:301–314.
Southern, E.M. 1975. Detection of specific sequences among DNA fragments separated by gel electrophoresis. Journal of Molecular Biology 98:503–517.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1981 Springer Science+Business Media New York
About this chapter
Cite this chapter
Birge, E.A. (1981). Gene Splicing, the Production of Artificial DNA Constructs. In: Bacterial and Bacteriophage Genetics. Springer Series in Microbiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-1749-5_14
Download citation
DOI: https://doi.org/10.1007/978-1-4757-1749-5_14
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4757-1751-8
Online ISBN: 978-1-4757-1749-5
eBook Packages: Springer Book Archive