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Pressure-Flow-Volume Relationships in the Normal Human Pulmonary Circulation at Sea-Level and at Altitude

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Pulmonary Circulation in Health and Disease

Part of the book series: Ettore Majorana International Science Series ((EMISS,volume 3))

Abstract

Doctor Lee showed us this morning beautiful data about pul satility of blood flow in the pulmonary circulation. That pulmonary blood flow is pulsatile in arteries, (1) and capillaries (2,3) is well documented. The distribution of blood volume in the different series components of the pulmonary circulation varies continuously throughout the heart cycle with a large fraction of right ventricular stroke volume being stored during systole in the arteries from which it runs off in to the capillaries and veins during diastole (4). Finally since ventilatory action also affects the pulmonary circulation, through its effects on both intrathoracic pressure and venous return (3,5,6), it may seem naive to continue studying the relationships between mean pulmonary blood volume (PBV), mean pulmonary blood flow (Q), mean pulmonary inflow (arterial) and outflow (left atrial or pulmonary wedge) pressure (Ppa and Pw respectively) whose respective values are averaged over several respiratory cycles and more cardiac cycles.

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Author information

Authors and Affiliations

  1. Laboratoire d’explorations fonctionelles, Hôpital Antoine Béclère, 92141, Clamart, France

    Alain Lockhart

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  1. Alain Lockhart
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Editor information

Editors and Affiliations

  1. The Midhurst Medical Research Institute, Midhurst, Sussex, UK

    G. Cumming

  2. University of Palermo, Palermo, Italy

    G. Bonsignore

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© 1980 Springer Science+Business Media New York

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Lockhart, A. (1980). Pressure-Flow-Volume Relationships in the Normal Human Pulmonary Circulation at Sea-Level and at Altitude. In: Cumming, G., Bonsignore, G. (eds) Pulmonary Circulation in Health and Disease. Ettore Majorana International Science Series, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1721-1_24

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  • DOI: https://doi.org/10.1007/978-1-4757-1721-1_24

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1723-5

  • Online ISBN: 978-1-4757-1721-1

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