Pressure-Flow-Volume Relationships in the Normal Human Pulmonary Circulation at Sea-Level and at Altitude

  • Alain Lockhart
Part of the Ettore Majorana International Science Series book series (EMISS, volume 3)


Doctor Lee showed us this morning beautiful data about pul satility of blood flow in the pulmonary circulation. That pulmonary blood flow is pulsatile in arteries, (1) and capillaries (2,3) is well documented. The distribution of blood volume in the different series components of the pulmonary circulation varies continuously throughout the heart cycle with a large fraction of right ventricular stroke volume being stored during systole in the arteries from which it runs off in to the capillaries and veins during diastole (4). Finally since ventilatory action also affects the pulmonary circulation, through its effects on both intrathoracic pressure and venous return (3,5,6), it may seem naive to continue studying the relationships between mean pulmonary blood volume (PBV), mean pulmonary blood flow (Q), mean pulmonary inflow (arterial) and outflow (left atrial or pulmonary wedge) pressure (Ppa and Pw respectively) whose respective values are averaged over several respiratory cycles and more cardiac cycles.


Pulmonary Vein Pulmonary Vascular Resistance Pulmonary Arterial Pressure Pulmonary Circulation Pulmonary Blood Flow 
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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Alain Lockhart
    • 1
  1. 1.Laboratoire d’explorations fonctionellesHôpital Antoine BéclèreClamartFrance

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