Pulmonary Diffusing Capacity for O2 and CO by Rebreathing Techniques Using Stable Isotopes

  • M. Meyer
  • P. Scheid
  • J. Piiper
Part of the Ettore Majorana International Science Series book series (EMISS, volume 3)


It is generally held that the alveolar-capillary membrane is not a significant limiting factor to oxygen transport in normal lungs of resting man at sea level. It is also well established that diffusion limitation becomes increasingly important in hypoxia. Therefore, the diffusive conductance or diffusing capacity of the lung (DL) must be finite and is expected to limit maximal O2 uptake in extreme conditions such as high altitude hypoxia.


Dissociation Curve Diffuse Capacity Pulmonary Blood Flow Mixed Venous Blood Equilibration Kinetic 
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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • M. Meyer
    • 1
  • P. Scheid
    • 1
  • J. Piiper
    • 1
  1. 1.Abteilung PhysiologieMax-Planck-Institut für experimentelle MedizinGöttingenGermany

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