Ion-Coupled Transport across Biological Membranes

  • Stanley G. Schultz

Abstract

Only a rudimentary understanding of the principles of classical thermodynamics is needed to appreciate that the flow of an uncharged substance from a region of lower concentration to a region of higher concentration or the flow of a charged substance from a region of lower electrochemical potential to a region of higher electrochemical potential cannot take place unless the processes responsible for these flows are linked or coupled to a supply of energy. Such flows, loosely referred to as “active” or “uphill,” are commonplace in biological systems and the thrust of many investigations is to identify the immediately responsible source(s) of energy.

Keywords

Amino Acid Transport Renal Proximal Tubule Ehrlich Ascites Tumor Cell Electrical Potential Difference Couple Solute 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Stanley G. Schultz
    • 1
  1. 1.Department of PhysiologyUniversity of Pittsburgh, School of MedicinePittsburghUSA

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