Na and K Transport in Red Blood Cells

  • Philip B. Dunham
  • Joseph F. Hoffman


This chapter on active transport is intended to be a rather practical treatment of the subject in terms of what active transport is, how it can be distinguished from other types of membrane transport, and a survey of its characteristics in some depth. The idea of active transport stems from the fact that cells are able to accumulate and maintain large concentration gradients of permeant substances across their plasma membranes. Because of the ubiquitous occurrence of such processes in living cells and tissues, our purpose can best be served by limiting our discussion to the active transport of the cations, Na and K, and using information derived mainly from studies on red blood cells. Thus, it is hoped that our considerations of basic principles in one cell type will emphasize those features common to all cell types rather than those differences which distinguish one cell type from another.


Active Transport Sodium Pump Ouabain Binding Cardiotonic Steroid Impermeant Anion 
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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Philip B. Dunham
    • 1
  • Joseph F. Hoffman
    • 2
  1. 1.Department of BiologySyracuse UniversitySyracuseUSA
  2. 2.Department of PhysiologyYale University School of MedicineNew HavenUSA

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