The Anatomy of Biological Interfaces

  • J. David Robertson


It is generally recognized that biological membranes have a common, basic lipid bilayer structure(179,180,191,193,231) which contains external, internal, and transmembrane proteins with chemical asymmetry as a fundamental feature(215–217); the asymmetry involves both lipids and proteins (see Rothman and Lenard(201) for a recent review). Certain glycoproteins such as glycophorin in erythrocyte membranes(146,207) are arranged with a protein moiety in the internal leaflet connected to a glycoprotein moiety in the external leaflet.(241) In the case of glycophorin, the internal and external moieties are connected by a stretch of hydrophobic amino acid residues traversing the bilayer probably as an α helix.


Lipid Bilayer Basic Protein Lipid Monolayer Unit Membrane Purple Membrane 
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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • J. David Robertson
    • 1
  1. 1.Department of AnatomyDuke University Medical CenterDurhamUSA

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