Primary Coccidioidomycosis

  • Antonino Catanzaro
  • David J. Drutz
Part of the Current Topics in Infectious Disease book series (CTID)


That approximately 60% of coccidioidal infections are asymptomatic has been discussed in Chapter 4. Forty percent of patients are symptomatic with a disease spectrum ranging from mild influenzalike complaints to frank pneumonia. Ordinarily the symptoms are sufficiently vague that no specific diagnosis is suggested. Thus, the epidemiologic history is of major value.


Pleural Fluid Complement Fixation Erythema Multiforme Erythema Nodosum Scarlet Fever 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    C. E. Smith, Epidemiology of acute coccidioidomycosis with erythema nodosum (“San Joaquin” or “Valley Fever”), Am. J. Public Health 30: 600–611 (1940).CrossRefGoogle Scholar
  2. 2.
    E. C. Dickson, “Valley Fever” of the San Joaquin Valley and fungus coccidioides, Calif. West. Med. 47: 151–155 (1937).Google Scholar
  3. 3.
    C. E. Smith, Diagnosis of pulmonary coccidioidal infections, Calif. Med. 75: 385–391 (1951).PubMedGoogle Scholar
  4. 4.
    H. K. Faber, C. E. Smith, and E. C. Dickson, Acute coccidioidomycosis with erythema nodosum in children, J. Pediat. 15: 163–171 (1939).CrossRefGoogle Scholar
  5. 5.
    C. E. Smith, Coccidioidomycosis, Med. Clin. North Am. 27: 790–807 (1943).Google Scholar
  6. 6.
    S. B. Werner and D. Pappagianis, Coccidioidomycosis in northern California. An outbreak among archeology students near Red Bluff, Calif. Med. 119: 16–20 (1973).PubMedGoogle Scholar
  7. 7.
    S. B. Werner, D. Pappagianis, I. Heindl, and A. Mickel, An epidemic of coccidioidomycosis among archeology students in northern California, N. Engl. J. Med. 286: 507–512 (1972).PubMedCrossRefGoogle Scholar
  8. 8.
    W. C. Harvey and W. H. Greendyke, Skin lesions in acute coccidioidomycosis, Am. Fam. Physician. 2: 81–85 (1970).Google Scholar
  9. 9.
    S. B. Werner, Coccidioidomycosis misdiagnosed as contact dermatitis. Calif. Med. 117: 59–61 (1972).PubMedGoogle Scholar
  10. 10.
    D. G. Ramras, H. A. Walch, J. P. Murray, and B. H. Davidson, An epidemic of coccidioidomycosis in the Pacific Beach area of San Diego, Am. Rev. Resp. Dis. 101: 975–978 (1970).PubMedGoogle Scholar
  11. 11.
    H. B. Richardson, Jr., J. A. Anderson, and B. M. McKay, Acute pulmonary coccidioidomycosis in children, J. Pediatr. 70: 376–382 (1967).PubMedCrossRefGoogle Scholar
  12. 12.
    M. J. Fiese, Coccidioidomycosis, Charles C. Thomas, Springfield, Ill. (1958).Google Scholar
  13. 13.
    E. C. Dickson, Coccidioidomycosis-The preliminary acute infection with fungus coccidioides, J. Am. Med. Assoc. 111: 1362–1365 (1938).CrossRefGoogle Scholar
  14. 14.
    E. C. Dickson and M. A. Gifford, Coccodioides infection (coccidioidomycosis). II. The primary type of infection, Arch. Intern. Med. 62: 853–871 (1938).CrossRefGoogle Scholar
  15. 15.
    C. E. Smith, Coccidioidomycosis. Pediatr. Clin. North Am. 2: 109–125 (1955).Google Scholar
  16. 16.
    D. M. Goldstein and S. Louie, Primary pulmonary coccidioidomycosis—Report of an epidemic of seventy-five cases, War Med. 4: 299–317 (1943).Google Scholar
  17. 17.
    F. M. Willett and A. Weiss, Coccidioidomycosis in southern California: Report of a new endemic area with a review of 100 cases, Ann. Intern. Med. 23:349–375 (1945).Google Scholar
  18. 18.
    R. A. Carter, Infectious granulomas of bones and joints, with special reference to coccidioidal granuloma, Radiology 23: 1–16 (1934).Google Scholar
  19. 19.
    C. E. Smith, R. R. Beard, E. G. Whiting, and H. G. Rosenberger, Varieties of coccidioidal infection in relation to the epidemiology and control of the diseases, Am. J. Public Health 36: 1394–1402 (1946).CrossRefGoogle Scholar
  20. 20.
    C. E. Smith, E. G. Whiting, E. E. Baker, H. G. Rosenberger, R. R. Beard, and M. T. Saito, The use of coccidioidin, Am. Rev. Tuberc. 57: 330–360 (1948).PubMedGoogle Scholar
  21. 21.
    E. F. Rosenberg, M. B. Dockerty, and H. W. Meyerding, Coccidioidal arthritis. Report of a case in which the ankles were involved and the condition was unaffected by sulfanilamide and roentgen therapy, Arch. Intern. Med. 69: 238–250 (1942).CrossRefGoogle Scholar
  22. 22.
    E. Alpert, K. J. Isselbacher, and P. H. Schur, The pathogenesis of arthritis associated with viral hepatitis. Complement-component studies, N. Engl. J. Med. 285: 185–189 (1971).PubMedCrossRefGoogle Scholar
  23. 23.
    E. C. Dickson, Primary coccidioidomycosis—The initial acute infection which results in coccidioidal granuloma, Am. Rev. Tuberc. 38: 722–729 (1938).Google Scholar
  24. 24.
    F. M. Willett, and E. Opperheim, Pulmonary infiltration with associated eosinophilia, Am. J. Med. Sci. 212: 606–612 (1946).CrossRefGoogle Scholar
  25. 25.
    J. W. Birsner, The roentgen aspects of five hundred cases of pulmonary coccidioidomycosis, Am. J. Roentgenol. Radium. Ther. Nucl. Med. 72: 556–573 (1954).PubMedGoogle Scholar
  26. 26.
    W. H. Greendyke, D. I. Resnick, and W. C. Harvey, The varied roentgen manifestations of primary coccidioidomycosis, Am J. Roentgenol. Radium. Ther. Nucl. Med. 109: 491–499 (1970).PubMedCrossRefGoogle Scholar
  27. 27.
    H. E. Einstein, Bilateral hilar adenopathy, Ann. Int. Med. 78: 787 (1973).PubMedCrossRefGoogle Scholar
  28. 28.
    H. W. Jamison, A roentgen study of chronic pulmonary coccidioidomycosis, Am. J. Roentgenol. 55: 396–412 (1946).Google Scholar
  29. 29.
    C. F. Sweigert, J. W. Turner, and J. B. Gillespie, Clinical and roentgenologic aspects of coccidioidomycosis, Am. J. Med. Sci. 212: 652–673 (1946).PubMedCrossRefGoogle Scholar
  30. 30.
    S. A. Lonky, A. Catanzaro, K. M. Moser, and H. Einstein, Acute coccidioidal pleural effusion, Am. Rev. Resp. Dis. 114: 681–688 (1976).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Antonino Catanzaro
  • David J. Drutz

There are no affiliations available

Personalised recommendations