Chemotherapy of Coccidioidomycosis

  • David A. Stevens
Part of the Current Topics in Infectious Disease book series (CTID)


Therapy of the various manifestations of coccidioidal disease has been discussed in the pertinent chapters. In this chapter the few drugs available for therapy of the disease are discussed, along with some general therapeutic guidelines.


Renal Tubular Acidosis Systemic Fungal Infection Chronic Mucocutaneous Candidiasis Peak Blood Level Coccidioidal Meningitis 
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  1. 1.
    J. M. T. Hamilton-Miller, Chemistry and biology of the polyene macrolide antibiotics, Bacteriol. Rev. 37: 166–196 (1973).Google Scholar
  2. 2.
    M. S. Collins and D. Pappagianis, Uniform susceptibility of various strains of Coccidioides immitis to amphotericin B, Antimicrob. Agents Chermother. 11: 1049–1055 (1977).CrossRefGoogle Scholar
  3. 3.
    R. M. Lawrence and P. D. Hoeprich, Comparison of amphotericin B and amphotericin B methyl ester: efficacy in murine coccidioidomycosis and toxicity, J. Infect. Dis. 133: 168–174 (1976).PubMedCrossRefGoogle Scholar
  4. 4.
    D. A. Stevens, Miconazole in the treatment of systemic fungal infections, Am. Rev. Resp. Dis. 116: 801–806 (1977).PubMedGoogle Scholar
  5. 5.
    D. Borelli, J. L. Bran, J. Fuentes, R. Legendre, E. Leiderman, H. B. Levine, A. Restrepo–M., and D. A. Stevens, Ketoconazole, an oral antifungal: laboratory and clinical assessment of imidazole drugs, Postgrad. Med. J. 55: 657–661 (1979).PubMedCrossRefGoogle Scholar
  6. 6.
    H. B. Levine, S. M. Ringel, and J. M. Cobb, Therapeutic properties of oral ambruticin (W7783) in experimental pulmonary coccidioidomycosis of mice, Chest 73: 202–206 (1978).PubMedCrossRefGoogle Scholar
  7. 7.
    H. B. Levine, R34,000, a dioxolane imidazole in the therapy of experimental coccidioidomycosis, Chest 70: 755–759 (1976).PubMedCrossRefGoogle Scholar
  8. 8.
    M. S. Collins and D. Pappagianis, Treatment of murine coccidioidomycosis with polymyxin B, Antimicrob. Agents Chemother. 10: 318–321 (1976).PubMedCrossRefGoogle Scholar
  9. 9.
    M. Huppert, S. H. Sun, and K. R. Vukovich, Combined amphotericin B—tetracycline therapy for experimental coccidioidomycosis, Antimicrob. Agents Chemother. 5: 473–478 (1974).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • David A. Stevens

There are no affiliations available

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