Pathology of the Kidney in Essential (Spontaneous) Hypertension

  • Anil K. Mandal


The anatomic pathology of the kidney in hypertension and the relationships between the clinical entity and the morphological changes in cortex and medulla of the kidney are presented in two separate parts. In Part 1, the changes in different components of the cortex and their relationship to different types of clinical hypertensions are described. The data from experimental studies are presented to clarify ambiguities. In Part 2, analyses of papillary interstitial cells and granules in normotensive humans and animals and in hypertensive animals are described. The role of the papillary interstitial cells and granules in guarding against hypertension is explored.


Smooth Muscle Cell Essential Hypertension Interstitial Cell Glomerular Basement Membrane Renal Lesion 
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Part 1

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Part 2

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Copyright information

© Springer Science+Business Media New York 1979

Authors and Affiliations

  • Anil K. Mandal
    • 1
  1. 1.Renal Electron Microscopy Laboratory and Staff Physician, Medical Service Veterans Administration HospitalUniversity of Oklahoma College of MedicineOklahoma CityUSA

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