Accomplishments of Electron Microscopy Study in the Practice of Nephrology
The practice of nephrology (renal medicine) involves mainly those patients with the nephrotic syndrome, the acute syndrome of diffuse proliferative glomerulonephritis, acute uremia, chronic uremia, asymptomatic proteinuria, recurrent microscopic hematuria, and hypertension. A safe method of obtaining a 1- to 2-cm core of renal tissue by means of closed needle biopsy and the increasing availability of electron microscopy (EM) techniques for evaluation of the renal tissue have popularized EM study among clinicians and pathologists in the practice of nephrology. There is little argument concerning the value of EM of renal tissue in patients with the nephrotic syndrome, but controversies still exist as to whether or not EM study is of clinical benefit in other renal diseases.
KeywordsNephrotic Syndrome Glomerular Basement Membrane Light Microscopy Study Congenital Nephrotic Syndrome Membranous Glomerulonephritis
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