Relative Size and Dispersity of Isolated Chromaffin Granules

  • D J Green
  • D B Sattelle
  • E W Westhead
  • K H Langley
Part of the Nato Advanced Study Institutes Series book series (NSSB, volume 23)


Chromaffin granules of the adrenal medulla are membrane bound vesicles containing proteins, ATP, adrenalin and noradrenalin. The release of the granules’ contents occurs by exocytosis subsequent to the fusion of the granule and the chromaffin cell membrane.1 However, the mechanism by which the granules are rapidly brought into contact with the cell membrane is not known. The surface properties of the granules are assumed to play an important role in this mechanism.2


Chromaffin Cell Adrenal Medulla Magnetic Tape Large Granule Chromaffin Granule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    W.W. Douglas, Brit J Pharmacol, 34, 451, 1968.CrossRefGoogle Scholar
  2. 2.
    P.M. Dean and E.K. Matthews, Biochem J. 142, 637, 1974.Google Scholar
  3. 3.
    J.M. Trifaro and J. Dworkind, Analyt Biochem. 34, 403, 1970.CrossRefGoogle Scholar
  4. 4.
    W. Edwards, J.H. Phillips and S.J. Morris, B.B.A. 356, 164, 1974.Google Scholar
  5. 5.
    F. Lishajko, Acta Physiol Scand Supp. 362, 1971.Google Scholar
  6. 6.
    H. Winkler, Phil Trans Roy Soc.Lond. B, 261, 273, 1971.ADSCrossRefGoogle Scholar
  7. 7.
    S.J. Morris, W. Edwards and J.H. Phillips, FEBS Letters, 44, 217, 1974.CrossRefGoogle Scholar
  8. 8.
    P.M. Dean, Stud. Biophys. Band 43, 227, 1974.Google Scholar
  9. 9.
    N.C. Ford, Jr., R. Gabler, and F.E. Karasz, Advan Chem. 125, 25, 1973.CrossRefGoogle Scholar
  10. 10.
    R. Asch and N.C. Ford, Jr., Rev. Sci Inst. 44, 506, 1973.ADSCrossRefGoogle Scholar
  11. 11.
    N.C. Ford, Jr., Chem Scripta, 2, 193, 1972.Google Scholar
  12. 12.
    P. Pusey in Photon Correlation and Light Beating Spectroscopy edited by H.Z. Cummins and E.R. Pike (Plenum, New York), 1974.Google Scholar

Copyright information

© Springer Science+Business Media New York 1977

Authors and Affiliations

  • D J Green
    • 1
  • D B Sattelle
    • 1
  • E W Westhead
    • 1
  • K H Langley
    • 1
  1. 1.Depts. of Physics and BiochemistryUniversity of MassachusettsAmherstUSA

Personalised recommendations