Photochemical Addition of Amino Acids and Related Compounds to Nucleic Acid Constituents

  • Alummutil J. Varghese


The most vital cell constituents of all living systems are the nucleic acids. Consequently, alterations in nucleic acid molecules are of utmost biological significance. These alterations can be either addition of molecules to nucleic acids or degradation of purine, pyrimidine, or sugar phosphate residues. From a biological point of view, the former type of alteration is of greater significance and it is the subject of this symposium. As shown by Smith (1975) in his review, a wide variety of compounds add to nucleic acids and their constituents under the influence of radiation (UV, visible, and ionizing).


Addition Product Pyrimidine Base Pyrimidine Dimer Maleic Hydrazide Hydroxy Compound 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • Alummutil J. Varghese
    • 1
  1. 1.Physics DivisionOntario Cancer InstituteTorontoCanada

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