The Role of the Environment in Chemical Reactions
The last decade has seen a renaissance in the study, both experimental and theoretical, of chemical reactions in solution1, 2. Naturally, a focus of these studies is the determination of the role of the solvent in affecting the rate constant for the chemical process. Here we attempt to give a very brief glimpse at some of the ideas and results that have emerged. We restrict the discussion exclusively to reactions in solution (and even then, to a very few topics). But it is likely that, at least in a general way, similar ideas should ultimately prove useful in the context of understanding enzyme catalysis rates.
KeywordsTransition State Reaction Coordinate Transition State Theory Nucleophilic Displacement Generalize Langevin Equation
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