Enzyme Catalysis: An Overview from Physics
The organizers of this workshop asked me, as the first speaker, to present “a broad overview/introduction/philosophy-like oriented lecture, as it appears that many of our collegues still have problems accepting the idea that a theoretical model can be of any use”. I have accepted their invitation gladly, but let me say at the start that I share some of the perplexities of my colleagues, and that I am not so naive as to believe that “our ultimate goal must be to develop a general and practically useful model of the total enzyme catalysis process”, as it is mentioned among the aims of this NATO-ASI. In the following, I will try to convince you that instead of a model we would do better to focus on a few general physical features of the process in question, each of these features coming into play with different emphasis in specific cases met in the laboratory.
KeywordsPercolation Threshold Enzyme Catalysis Thermal Bath Purple Membrane Proton Movement
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