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Simple Systems with Interactions

  • Arieh Ben-Naim

Abstract

In this chapter we introduce interactions among the particles of the system. These interactions are simple enough so that the treatment of the system by ST is still feasible. The models presented in the following sections are devised to mimic the behavior of binding or adsorption phenomena frequently occurring in biochemistry. Examples are the binding of oxygen to hemoglobin, the binding of ligands to multisubunit enzymes, the so-called allosteric effect, and the far more complex binding of proteins, such as repressors, to DNA.

Keywords

Average Force Simple System Conformational State Pair Correlation Function Regulatory Curve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    J. Monod, J. Wyman, and J. P. Changeux, J. Mol. Biol., 12, 88 (1965).CrossRefPubMedGoogle Scholar
  2. 2.
    D. Koshland, G. Némethy, and D. Filmer, Biochemistry, 5, 365 (1966).CrossRefPubMedGoogle Scholar

Suggested Reading

  1. T. L. Hill, Cooperativity Theory in Biochemistry, Steady State and Equilibrium Systems ( Springer-Verlag, New York, 1985 ).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Arieh Ben-Naim
    • 1
  1. 1.Department of Physical ChemistryThe Hebrew University of JerusalemJerusalemIsrael

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