Abstract
Although it has been well established for two decades that the human pineal gland produces and secretes melatonin, and although investigators began describing effects of exogenous melatonin on humans (principally on sleepiness and subjective vigor) soon after its discovery, relatively little information has been available until recently about the normal range of melatonin concentrations in human plasma and other body fluids, and even less about the effects of exogenous melatonin or its roles in human physiological processes.
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Wurtman, R.J., Waldhauser, F., Lieberman, H.R. (1983). The Secretion and Effects of Melatonin in Humans. In: Axelrod, J., Fraschini, F., Velo, G.P. (eds) The Pineal Gland and its Endocrine Role. NATO Advanced Science Institutes Series, vol 65. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1451-7_29
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