Activation of Mononuclear Phagocytes for the Destruction of Intracellular Parasites: Studies with Trypanosoma cruzi

  • Nadia Nogueira
  • Zanvil A. Cohn
Part of the Contemporary Topics in Immunobiology book series (CTI, volume 13)


Trypanosoma cruzi is an obligate intracellular parasite of man and other mammals. In man, it produces a chronic infection which, in its more severe form, leads to cardiac damage and failure (Chagas disease).


Macrophage Activation Mononuclear Phagocyte Trypanosoma Cruzi Reactive Oxygen Intermediate Parasitophorous Vacuole 
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • Nadia Nogueira
    • 1
  • Zanvil A. Cohn
    • 1
  1. 1.Department of Cellular Physiology and ImmunologyThe Rockefeller UniversityNew YorkUSA

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