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Receptors and Aging

  • Chapter
Aging and Cell Function

Abstract

Recent years have seen major advances in neuroendocrinology, neurobiology, and membrane biochemistry. Hormone and neurotransmitter receptors were poorly understood and many were unknown until a few years ago. During the past decade there has been a growing realization that neurotransmitters convey nerve impulses and that hormone receptors ultimately convey “messages” to cellular control centers (Pradham, 1980; Cuatrecases, 1974). While some researchers have attempted to document the age-related deterioration of physiological control systems in a general way, this study considers the role of hormone and neurotransmitter receptors in the age-related dysfunctions of once “finely tuned” control systems. Current studies of age changes in receptors come from such diverse fields as pharmacology, neuroendocrinology, and experimental psychology. These and related subdisciplines are becoming increasingly aware of the importance of such studies viewed from a gerontological perspective.

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Authors and Affiliations

  1. Department of Natural Sciences, Messiah College, Grantham, Pennsylvania, 17027, USA

    Gerald D. Hess

  2. National Institute on Aging, National Institutes of Health, Gerontology Research Center, Baltimore City Hospitals, Baltimore, Maryland, 21224, USA

    George S. Roth

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  1. Gerald D. Hess
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Editors and Affiliations

  1. Department of Neurology, Johns Hopkins University School of Medicine, 21205, Baltimore, Maryland, USA

    John E. Johnson Jr.

  2. National Institute on Aging, National Institutes of Health, Baltimore City Hospitals, 21224, Baltimore, Maryland, USA

    John E. Johnson Jr.

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Hess, G.D., Roth, G.S. (1984). Receptors and Aging. In: Johnson, J.E. (eds) Aging and Cell Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1430-2_2

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