Phosphatidyl Choline and Lysophosphatidyl Choline in Mixed Lipid Micelles as Novel Drug Delivery Systems

  • David W. Yesair


Since the early nineteen seventies, considerable research effort has been focused on the merits of using delivery systems for improving the efficiency and safety of drugs and thus realizing a higher percentage of the commercial market. Some of the projected benefits of drug delivery systems are summarized in Table 1. Of primary importance, drug delivery systems must enhance the quality of practiced medicine. For example, drug delivery systems can increase the therapeutic benefits by minimizing side effects, by increasing the efficacies, by decreasing the amount and frequency of dosing, by enhancing absorption and by affecting parameters such as the palatability and stability of the drug. Further, the drug delivery system can affect the biodegradation of drugs within the milieu of the G.I. tract and during passage through the intestine and liver. Lastly, drug delivery systems can make drugs categorically more useful.


Bile Salt Drug Delivery System High Density Lipoprotein Phosphatidyl Choline Polar Head Group 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • David W. Yesair
    • 1
  1. 1.BioMolecular Products, Inc.ByfieldUSA

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