Phospholipids pp 167-176 | Cite as

The Effect of Phospholipids and Lipotropic Factors on Xenobiotic Toxicity

  • G. Caderni


Although fat is an essential component of the diet, epidemiological and experimental studies indicate that a high intake of fat increases the risk of developing colon cancer (2,34,25). To explain this correlation it has been suggested that dietary fat damages the intestinal mucosa leading to an increased proliferation of the colonic cells (11,33). Hyperproliferation has been associated with an increased risk of developing colon cancer both in experimental animals and humans (20).


Colonic Mucosa Complete Diet Choline Bitartrate Develop Colon Cancer Chronic Feeding 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • G. Caderni
    • 1
  1. 1.Department of Preclinical and Clinical PharmacologyUniversity of FlorenceFlorenceItaly

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