Phospholipids pp 133-165 | Cite as

Therapeutic Aspects of Liposomes

  • F. Puisieux
  • G. Barratt
  • L. Roblot-Treupel
  • J. Delattre
  • P. Couvreur
  • J. Ph. Devissaguet


The fate of a drug after administration in vivo is determined by a combination of several processes: distribution and elimination when given intravenously and absorption, distribution and elimination when an extravascular route is used. Regardless of the mechanisms involved, each of these processes depends mainly on the physico-chemical properties of the drug and therefore, for the most part, on its chemical structure.


Visceral Leishmaniasis Drug Carrier Liposomal Amphotericin Systemic Fungal Infection Free Doxorubicin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations used




amphotericin B


cytosine arabinoside


adenosine triphosphate
















diethylene triamine pentaacetic acid




multilamellar vesicles




oleic acid






recombinant human interferon


reticuloendothelial system


reverse phase vesicles






small unilamellar vesicles


phase transition temperature


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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • F. Puisieux
    • 1
  • G. Barratt
    • 1
  • L. Roblot-Treupel
    • 1
  • J. Delattre
    • 1
    • 2
  • P. Couvreur
    • 1
  • J. Ph. Devissaguet
    • 1
  1. 1.Laboratoire de Pharmacie Galénique et de Biopharmacie, URA CNRS 1218Université de Paris XIChâteany-Malabry CédexFrance
  2. 2.Laboratoire de BiochimieUniversité de Paris VParisFrance

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