How to set up a Bilayer System

  • Osvaldo Alvarez


In this chapter I explain how to set up a planar bilayer system. The aim is to guide investigators taking their initial steps in the bilayer field in making their first setup. The intention is to give practical guidance rather than a thorough theoretical treatment of the different subjects. I assume that the reader has minimal knowledge of electronics and is planning to build the equipment.


Step Response Operational Amplifier Membrane Formation Membrane Capacitance Bilayer System 
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  1. Alvarez, O., Benos, D., and Latorre, R., 1985, The study of ionic channels in planar lipid bilayer membranes, J. Electrophysiol. Tech. 12:159–178.Google Scholar
  2. Sigworth, F., 1983, Electronic design of the patch clamp, in: Single-Channel Recording (B. Sakmann and E. Neher, eds.), pp. 3–35, Plenum Press, New York.CrossRefGoogle Scholar


  1. Burr-Brown Product Data Book, 1984, Burr-Brown, Tucson, Arizona.Google Scholar
  2. Data Acquisition components and Subsystems, 1980, Analog Devices, Norwood, Massachusetts.Google Scholar
  3. Signetics Analog Manual, 1976, Signetics Corporation, Sunnyvale, California.Google Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Osvaldo Alvarez
    • 1
    • 2
  1. 1.Departamento de Biologìa, Facultad de CienciasUniversidad de ChileSantiagoChile
  2. 2.Centro de Estudios Cientificos de SantiagoSantiagoChile

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