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Nutritional Biochemistry and Pathology pp 473–485Cite as

Dietary Fiber, Bile Acids and Cholesterol Metabolism

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Part of the book series: Nutrition and Food Science ((NFS,volume 3))

Abstract

There is considerable evidence that high dietary fiber intake is associated with a reduced incidence of ischemic heart disease in humans1, 4 and a reduced rate of atheroma development in laboratory animals5, 7. Experimental approaches to elucidate the underlying mechanisms of these effects have yielded inconsistent results both with natural fiber, such as wheat bran, and with purified fiber components like cellulose4, 7. This has been due, in part, to the criteria employed to determine the physiological response to changing fiber content of the diet, and in part, to the composition of the diets themselves. In some cases, the determination of serum of liver cholesterol levels, for example, has not permitted definitive conclusions regarding the overall effects of dietary fiber, since in the human, and in experimental animals like the rat, there are efficient homeostatic mechanisms for regulating circulating sterol levels.

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Authors and Affiliations

  1. Dept. of Biochemistry, The George Washington University, 2300 Eye Street N.W., Washington, D.C., 20037, USA

    G. V. Vahouny

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  1. G. V. Vahouny
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Editors and Affiliations

  1. Brazilian Nutrition Society, Rio de Janeiro, Brazil

    Walter Santos , Nabuco Lopes , J. J. Barbosa  & Dagoberto Chaves , ,  & 

  2. National Food and Nutrition Institute and Associação Brasiliense de Nutrologia, Rio de Janeiro, Brazil

    José Carlos Valente

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© 1980 Springer Science+Business Media New York

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Vahouny, G.V. (1980). Dietary Fiber, Bile Acids and Cholesterol Metabolism. In: Santos, W., Lopes, N., Barbosa, J.J., Chaves, D., Valente, J.C. (eds) Nutritional Biochemistry and Pathology. Nutrition and Food Science, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1349-7_58

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  • DOI: https://doi.org/10.1007/978-1-4757-1349-7_58

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1351-0

  • Online ISBN: 978-1-4757-1349-7

  • eBook Packages: Springer Book Archive

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