The Relation of Obesity to Cardiovascular Disease

  • F. X. Pi-Sunyer
Part of the Nutrition and Food Science book series (NFS, volume 3)


With the increasing prevalence of overweight in the technologically advanced countries has come a preoccupation with weight-control programs, and great amounts of money are being expended by obese patients to try to attain the magic goal of “desirable” body weight. In recent years, however, there has been considerable controversy about the actual effect of obesity on health and therefore about the necessity of preventive measures.


Coronary Heart Disease Angina Pectoris Relative Weight Excess Mortality Rheumatic Heart Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Society of Actuaries, 1959 Build and Blood Pressure Study, Chicago, IllGoogle Scholar
  2. 2.
    National Center for Health Statistics, Weight by Height and Age of Adults, United States, 1960–1962. Vital Health Statistics-PHS Publication No. 1000-Series 11, No. 14, May, 1960.Google Scholar
  3. 3.
    National Center for Health Statistics. Height and weight of adults 18–74 years of age in the United States. Advance Data from Vital and Health Statistics, No. 3, pp. 1–8, November 19, 1976.Google Scholar
  4. 4.
    Nutrition Canada National Survey, Nutrition: A National Priority, Information Canada Catalogue No. H 58–36, 1973, Ottawa, 1973.Google Scholar
  5. 5.
    Bjurulf, P. and Lindgren, G., in: Occurrence, Causes and Prevention of Overnutrition. Symposium of the Swedish Nutrition Foundation II. A Preliminary Study on Overweight in the South of Sweden, 1963, p. 9.Google Scholar
  6. 6.
    Walker, A.R.P. and Richardson, B.D., Overnutrition in Children. Lancet 2: 1146, 1971.CrossRefGoogle Scholar
  7. 7.
    Rimm, A.A., Controversies in Medicine-Is Obesity Harmful? Obesity/Bar. Med. 2: 140–144, 1973.Google Scholar
  8. 8.
    Build and Blood Pressure Study, 1959, Society of Actuaries, as derived in Mortality among overweight men. Stat. Bull. Metropol. Life Ins. Co. 41: 6 February, 1960 and in Mortality among overweight women. Stat. Bull. Metropl. Life Ins. Co. 41:1, March, 1960.Google Scholar
  9. 9.
    Build and Blood Pressure Study, 1959, Society of Actuaries, as derived in Overweights benefit from weight reduction. Stat. Bull. Metropol. Life Ins. Co. 41: 1, April, 1960.Google Scholar
  10. 10.
    Dublin, L.I., Relation of obesity to longevity. New England J. Med. 248: 971–974, 1953.CrossRefGoogle Scholar
  11. 11.
    Seltzer, C.C., Some re-evaluations of the Build and Blood Pressure Study, 1959, as related to ponderal index, somato type and mortality. New Eng. J. Mdd. 274: 254–259, 1966.CrossRefGoogle Scholar
  12. 12.
    Bray, J., “The Obese Patient”, W.B. Saunders & Co., Philadelphia 1976, p. 219.Google Scholar
  13. 13.
    Wilens, S.L., Bearing of general nutritional state on atherosclerosis. Arch. Int. Med. 79: 129–147, 1947.CrossRefGoogle Scholar
  14. 14.
    Wilkins, R.H., Roberts, J.C. Jr. and Moses, C., Autopsy studies in atherosclerosis. III. Distribution and severity of atherosclerosis in the presence of obesity, hypertension, nephrosclerosis and rheumatic heart disease. Circul. 220: 527–535, 1959.CrossRefGoogle Scholar
  15. 15.
    Faber, M. and Land, F., Human Aorta: influence of obesity on the development of arteriosclerosis in the human aorta. Arch. Path. 48: 351–361, 1949.Google Scholar
  16. 16.
    Spain, D.M., Bradess, V.A. and Huss, G.A., Observations on atheros- clerosis of the coronary arteries in males under the age of 46: A necropsy study with special reference to somato types. Ann. Intern. Med. 38: 254–277, 1953.CrossRefGoogle Scholar
  17. 17.
    Kannel, W.B. and Gordon, T., “Obesity and cardiovascular disease: The Framingham Study in Obesity”, Burland, W., Samuel, P.D. and Yudkin, J., eds., Churchill Livingstone, London, 1974.Google Scholar
  18. 18.
    Spain, D.M., Nathan, D.J. and Gellis, M., Weight, body types and the prevalence of coronary atherosclerotic heart disease in males. Amer. J. Med. Sci. 245: 63–69, 1963.CrossRefGoogle Scholar
  19. 19.
    Stamler, J., Berkson, D.M. and Lindberg, H.A., Coronary risk factors. Med. Clinic North America, 50: 229–254, 1966.Google Scholar
  20. 20.
    Dunn, J.P., Ipsen, J., Elsom, K.O., and Ohtani, M., Risk factors in coronary artery disease, hypertension and diabetes. Am. J. Med. Sci. 259: 309–322, 1970.CrossRefGoogle Scholar
  21. 21.
    Rosenman, R.H., Friedman, M., Straus, R., Jenkins, C.D., Zyzanski, S.J. and Wurm, M., Coronary heart disease in the Western collaborative group study. J. Chron. Dis. 23: 173–190, 1970.CrossRefGoogle Scholar
  22. 22.
    Chapman, J.M., Coulson, A.H., Clark, V.A., and Borun, E.R., The differential effect of serum cholesterol, blood pressure, and weight on the incidence of myocardial infarction and angina pectoris. J. Chron. Dis. 23: 631–645, 1971.CrossRefGoogle Scholar
  23. 23.
    Heyden, S., Cassel, J.C., Bartel, A., Tyroler, H.A., Hames, C.G. and Cornomi, J.C., Body weight and cigarette smoking as risk factors. Arch. Int. Med. 128: 915–920, 1971.CrossRefGoogle Scholar
  24. 24.
    Carlson, L.A., and Bottiger, L.E., Ischemic heart disease in relation to fasting values of plasma triglycerides and cholesterol. Stockholm prospective study. Lancet 1: 865–868, 1972.CrossRefGoogle Scholar
  25. 25.
    Keys, A., Aravanis, C., Blackburn, H. et al., Coronary heart disease: Overweight and obesity as risk factors. Ann. Int. Med. 77: 15–27, 1972.CrossRefGoogle Scholar
  26. 26.
    Kannel, W.B. and Gordon, T., Some determinants of obesity and its impact as a cardiovascular risk factor. In: “Recent Advances in Obesity Research: I”. A. Howard, ed., Newman Publishing Co., London, 1975, pp. 14–27.Google Scholar
  27. 27.
    Rabkin, S.W., Mathewson, R.A.L. and Hsu, P.H., Relation of body weight to development of ischemic heart disease in cohort of young North American men after a 26 year observation period: The Manitoba Study. Am. J. Cardiol. 39: 452–258, 1977.CrossRefGoogle Scholar
  28. 28.
    Kannel, W.B., Dawber, T.R., Kagan, A., et al., Factors of risk in the development of Coronary Heart Disease-6 year follow-up experience. The Framingham Study. Ann. Intern. Med. 55: 33–50, 1961.CrossRefGoogle Scholar
  29. 29.
    Chapman, J.M. and Massey, F.J., The interrelationship of serum cholesterol, hypertension, body weight and risk of coronary heart disease; results of first 10 year follow-up in Los Angeles Heart Study. J. Chron. Dis. 17: 933–999, 1964.CrossRefGoogle Scholar
  30. 30.
    Chiang, B.N., Perlman, L.V., Fulton, M., Ostrander, L.D., and Epstein, F.H., Predisposing factors in sudden cardiac death in Tecumseh, Michigan. Circul. 41: 31–37, 1970.CrossRefGoogle Scholar
  31. 31.
    Kannel, W.B., Le Bauer, El J., Dawber, T.R. and McNamara, P.M., Relation of body weight to development of coronary heart disease. Circul. 35: 734–744, 1967.CrossRefGoogle Scholar
  32. 32.
    Bjerkedal, T., Overweight and hypertension. Acta. Med. Scan. 159: 13–26, 1957.CrossRefGoogle Scholar
  33. 33.
    Gordon, T., Castellî, W.P., Hjortland, M.C., Kannel, W.B. and Dawber, T.R., Diabetes, blood lipids, and the role of obesity in coronary heart disease risk for women. Ann. Int. Med. 87: 393–397, 1977.CrossRefGoogle Scholar
  34. 34.
    Heyden, S., Haines, C.G., Bartel, S., et al., Weight and weight history in relation to cerebrovascular and ischemic heart disease. Arch. Intern. Med. 128: 956–960, 1971.CrossRefGoogle Scholar
  35. 35.
    Abraham, S., Collins, G. and Nordsieck, M., Relationship of childhood weight status to morbidity in adults. H.S.M.H.A. Health Reports 86: 273–284, 1971.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • F. X. Pi-Sunyer
    • 1
  1. 1.Dept. of MedicineSt. Luke’s Hospital CenterNew YorkUSA

Personalised recommendations