Significance of Steroid Receptor Immunoassay in Breast Cancer

  • Edward J. Keenan
  • Debra Corbin


Human breast cancers that contain estrogen (ER) and progesterone (PR) receptors are more likely to respond to antihormone therapy than are carcinomas that lack steroid receptors (1–10). This difference proviDe S the basis for the present use of ER and PR assays in determining the endocrine dependence of breast cancers (8–11). The absence of steroid receptors in breast carcinoma tissue is also of prognostic significance in that receptor-negative tumors generally recur more quickly (12–14).


Breast Cancer Estrogen Receptor Progesterone Receptor Human Breast Cancer Primary Breast Cancer 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Edward J. Keenan
    • 1
  • Debra Corbin
    • 1
  1. 1.Departments of Pharmacology, Surgery, and Medicine School of MedicineThe Oregon Health Sciences UniversityPortlandUSA

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