High Frequency of ras Oncogene Activation in Benign and Malignant Human Thyroid Tumours
Tumours of the follicular epithelium of the human thyroid gland represent a multi-stage model of epithelial tumorigenesis with a low frequency of malignant progression (Williams 1979). Human thyroid follicular adenomas are genuine benign neoplasms which occur much more frequently and affect a younger age group than follicular carcinomas (Sommers 1982) , while at the other end of the spectrum, undifferentiated thyroid carcinomas are rare tumours which occur predominantly in the elderly and are thought to arise as a progression from differentiated carcinoma.
KeywordsAcute Myeloid Leukemia Follicular Carcinoma Human Thyroid Undifferentiated Carcinoma Follicular Adenoma
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