Transcriptional Regulatory Sequences in the H-ras1 Gene

  • Derretrios A. Spandidos


The H-ras1 gene is a member of the ras family (1, 2). It is the smallest of the family occupying approximately 3.5 kb of DNA. It encodes a protein of 21, 000 daltons which possesses GDP and GTP binding and GTPase activities. The viral p21 also exhibits autophcephorylating activity. Although the function of the ras p21 proteins is not known they are assumed to be signal transducers because of their structural and functional similarities with G proteins (1,2).


Transcriptional Enhancer Cellular Oncogene Variable Tandem Repeat Human Breast Lesion Transcriptional Enhancer Activity 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Derretrios A. Spandidos
    • 1
    • 2
  1. 1.The Beatson Institute for Cancer ResearchGarscube EstateBearsden GlasgowScotland, UK
  2. 2.Biological Research CenterNational Hellenic Research FoundationAthensGreece

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