Structure and Organization of the ras Gene Family, in Human
The H-ras, K-ras and N-ras genes code for 21kd GTP/GDP binding proteins possessing a weak GTPase activity and transiently anchored to the inner face of the plasma membrane by a palmitic acid covalently linked to their C-terminus.
KeywordsGTPase Activate Protein Oligonucleotide Strategy
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- Olofsson, B., Chardin, P., Touchot, N., Zahraoui, A. and Tavitian A. (1988). Expression of the ras-related ralA, rhol2 and rab genes in adult mouse tissues. Oncogene, 2, 231–234.Google Scholar
- Pizon, V., Chardin, P., Lerosey, I., Olofsson B. and Tavitian A. (1988a). Human cDNAs rapl and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the “effector” region. Oncogene, 2, 201–204.Google Scholar
- Seuwen, K., Lagarde, A. and Pouyssegur, J. (1988). Deregulation of hamster fibroblast proliferation by mutated ras oncogenes is not mediated by constitutive activation of phosphoinositide-specific phospholipase. C. EMBO J. 7, 161–168.Google Scholar
- Willumsen, B.M., Papageorge, A.G., Kung, H.F., Bekesi, E., Robins, T., Johnsen, M., Vass, W.C., and Lowy, D.R. (1986). Mutational analysis of a ras catalytic domain. Mo. Cell. Biol., 6, 2646–2654.Google Scholar