A Discussion of Methods for Predicting Patients Who are Prone to Platelet Thromboembolism Including Measurements of Blood Components
The belief that aggregates of platelets may develop in the circulation and interfere with the vascular supply to vital organs is certainly not a new concept. It received further support from the observations of morphologists who found platelet aggregates as prominent components of thrombi and from studies in which the infusion of aggregating agents into local vascular beds caused organ injury or infarction in association with the formation of platelet aggregates. These lesions failed to develop if the animals were treated with inhibitors of platelet aggregation prior to the infusion of the aggregating agent.
KeywordsTransient Cerebral Ischemia Granulomatous Hepatitis Platelet Survival Recurrent Deep Vein Thrombosis Aggregate Test
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