• Edward A. MortimerJr.


Bordetella pertussis produces a single disease syndrome in man known as pertussis or whooping cough. Affecting children primarily, it characteristically displays a protracted course measured in weeks with the development of vigorous paroxysmal coughing, often associated with vomiting that sometimes results in inanition and occasionally with brain damage. At the turn of the century, it was a major cause of infant mortality worldwide. To a large extent due to immunization, it is at present of less consequence in developed countries such as the United States, but continues to be a major child health problem in developing nations.


Pertussis Toxin Tetanus Toxoid Pertussis Vaccine Whooping Cough Acellular Pertussis Vaccine 
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Suggested Reading

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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Edward A. MortimerJr.
    • 1
  1. 1.Departments of Epidemiology and Biostatistics and PediatricsCase Western Reserve University School of MedicineClevelandUSA

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