Control of the Coronary Circulation

  • Harvey V. SparksJr.
  • Roger D. Wangler
  • Donald F. Dewitt
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 34)


Normal function of the heart depends on an adequate coronary blood flow. Myocardial metabolism and coronary flow are mutually interactive so that any increase in the metabolism of the normal heart is matched by an increase in coronary blood flow, and any significant restriction of flow in pathophysiologic states results in the reduction of myocardial metabolism and cardiac performance. In this chapter we describe the determinants of coronary blood flow; these include physical factors, myocardial metabolism, humoral influences, and neural control. In addition, we discuss certain pathophysiologic conditions, such as vascular responses to cardiac hypertrophy and myocardial ischemia, and the significance of coronary collateral vessels.


Myocardial Blood Flow Coronary Blood Flow Reactive Hyperemia Coronary Circulation Myocardial Metabolism 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media Dordrecht 1984

Authors and Affiliations

  • Harvey V. SparksJr.
  • Roger D. Wangler
  • Donald F. Dewitt

There are no affiliations available

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