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Aging of the Adult Heart

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Physiology and Pathophysiology of the Heart

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 34))

Abstract

Both quantitative and qualitative assessment of normal cardiovascular function differ with age of the organism studied [1–4]. Thus, functional studies of the normal heart at a single age are incomplete and represent only a point on a continuum. A full understanding of heart function in stressful or pathologic states must consider that age-related changes modify the substrate upon which the stress or disease process is superimposed and that the expression of a given pathologic state is not solely due to the disease per se, but represents an age—disease interaction. Striking examples of this interaction can be observed in cardiac overload states [5] or in the effect of adaptation of the myocardium to chronic physical conditioning [6].

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Authors
  1. Edward G. Lakatta
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Editors and Affiliations

  1. Department of Physiology, University of Cincinnati Medical Center, 231 Bethesda Avenue, 45267, Cincinnati, Ohio, USA

    Nicholas Sperelakis

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© 1984 Springer Science+Business Media Dordrecht

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Lakatta, E.G. (1984). Aging of the Adult Heart. In: Sperelakis, N. (eds) Physiology and Pathophysiology of the Heart. Developments in Cardiovascular Medicine, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1171-4_27

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  • DOI: https://doi.org/10.1007/978-1-4757-1171-4_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1173-8

  • Online ISBN: 978-1-4757-1171-4

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