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Physiology and Pathophysiology of the Heart pp 459–476Cite as

Mechanism of Action of Antiarrhythmic Drugs

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Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 34))

Abstract

In this chapter we describe the modulated receptor hypothesis for the action of certain antiarrhythmic drugs. We briefly review the work that led to this hypothesis, present a detailed description of the mechanism, and apply it to a group of antiarrhythmic agents and the arrhythmias in which they are used.

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Authors
  1. Luc M. Hondeghem
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  2. Bertram G. Katzung
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Editors and Affiliations

  1. Department of Physiology, University of Cincinnati Medical Center, 231 Bethesda Avenue, 45267, Cincinnati, Ohio, USA

    Nicholas Sperelakis

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Hondeghem, L.M., Katzung, B.G. (1984). Mechanism of Action of Antiarrhythmic Drugs. In: Sperelakis, N. (eds) Physiology and Pathophysiology of the Heart. Developments in Cardiovascular Medicine, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1171-4_21

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  • DOI: https://doi.org/10.1007/978-1-4757-1171-4_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1173-8

  • Online ISBN: 978-1-4757-1171-4

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