Treatment for cancer has increasingly become more effective as indicated by the progressively longer survival of afflicted individuals. Consequently, comprehensive clinical management must address not only the medical status of the patient but, additionally, caretakers must be concerned with the person’s psychological condition and overall social adjustment. The patient’s emotional reactions, subjective feelings, functional behavioral capacity, interpersonal relationships, and psychosocial adjustment are encompassed by the multidimensional construct quality of life.


Acute Lymphocytic Leukemia Temporal Lobe Epilepsy Progressive Multifocal Leukoencephalopathy Childhood Leukemia Neuropsychological Evaluation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Abramson, N., Raben, M., and Cavanaugh, P. J. (1974). Brain tumors in children: Analysis of 136 cases. Radiology, 112, 669–672.PubMedGoogle Scholar
  2. Bamford, F. N., Jones, P. M., Pearson, D., Ribeiro, G. G., Shalet, S. M., and Beardwell, C. G. (1976). Residual disabilities in children treated for intracranial space-occupying lesions. Cancer, 37, 1149–1151.PubMedCrossRefGoogle Scholar
  3. Berg, R. A., Ch’ien, L. T., Bowman, W. P., Ochs, J., Lancaster, W., Goff, J. R., and Anderson, H. R., Jr. (1983). The neuropsychological effects of acute lymphocytic leukemia and its treatment—A three year report: Intellectual functioning and academic achievement. Clinical Neuropsychology, 5, 9–13.Google Scholar
  4. Berg, R. A., Tuseth, S., Ochs, J., and Cummins, J. (1984, August). Neuropsychological sequelae of acute lymphocytic leukemia and its treatment—A longitudinal study. Paper presented at the 92nd Annual Meeting of the American Psychological Association, Toronto, Canada.Google Scholar
  5. Berry, M. P., Jenkin, D. T., Keen, G. W., Nair, B. D., and Simpson, W. J. (1981). Radiation for medulloblastoma. Journal of Neurosurgery, 55, 43–51.PubMedCrossRefGoogle Scholar
  6. Binger, C. M., Ablin, A. R., Feuerstein, R. C., Kushner, J. H., Zoger, S., and Mikkelsen, C. (1969). Childhood leukemia: Emotional impact on patient and family. The New England Journal of Medicine, 280, 414–418.Google Scholar
  7. Bingley, T. (1958). Mental symptoms in temporal lobe epilepsy and temporal lobe glioma. Acta Psychiatrica et Neurologica Scandinavia, 120, 1–151.Google Scholar
  8. Bloom, H. J. G., Wallace, E. N. K., and Henk, J. M. (1969). The treatment and prognosis of medulloblastoma in children. American Journal of Roentgenology, 105, 43–62.Google Scholar
  9. Boll, T. J., and Barth, J. T. (1981). Neuropsychology of brain damage in children. In S. B. Filskov and T. J. Boll (Eds.), Handbook of clinical neuropsychology (pp. 418–452 ). New York: Wiley.Google Scholar
  10. Botez, M. I., and Wertheim, N. (1959). Expressive aphasia and amnesia following right frontal lesion in a right-handed man. Brain, 82, 186–202.PubMedCrossRefGoogle Scholar
  11. Bowman, W. P. (1981). Childhood acute lymphocytic leukemia: Progress and problems in treatment. CMA Journal, 124, 129–142.Google Scholar
  12. Brown, J. W. (1974). Aphasia, apraxia and agnosia: Clinical and theoretical aspects. Springfield, IL: Charles C Thomas.Google Scholar
  13. Chelune, G. J., and Edwards, P. (1981). Early brain lesions: Ontogenetic-environmental considerations. Journal of Consulting and Clinical Psychology, 49, 777–790.Google Scholar
  14. Chusid, J. G. (1973). Correlative neuroanatomy and functional neurology ( 15th ed. ). Los Altos, CA: Lange Medical Publications.Google Scholar
  15. Copeland, D. R., Fletcher, J. M., Pffefferbaum-Levine, B., Jaffe, N., Ried. H., and Maor, M. (1985). Long-term survivors of childhood cancer: Effects of CNS treatment. Pediatrics, 75, 745753.Google Scholar
  16. Corkin, S. (1965). Tactually guided maze learning in man Effects of unilateral cortical excisions and bilateral hippocampal lesions. Neuropsychologia, 3, 339–351.CrossRefGoogle Scholar
  17. Corkin, S., Milner, B., and Taylor, L. (1973). Bilateral sensory loss after unilateral cerebral lesion in man. Transactions of the American Neurological Association, 98, 118.Google Scholar
  18. Currie, S., and Henson, R. A. (1971). Neurological syndromes in the reticuloses. Brain, 94, 307310.Google Scholar
  19. D’Angio, G. J. ( 1980, November). Late sequelae after cure of childhood cancer. Hospital Practice, 109–121.Google Scholar
  20. Danoff, B., Cowchock, F., Marquette, C., Mulgrew, L., and Kramer, S. (1982). Assessment of longterm effects of primary radiation therapy for brain tumors in children. Cancer, 49, 1580 1586.Google Scholar
  21. Davies, J. A., Hughes, J. T., and Oppenheimer, D. R. (1973). Richardson’s disease (progressive multifocal leukoencephalopathy). Quarterly Journal of Medicine, 42, 481–489.PubMedGoogle Scholar
  22. Davison, K., and Bagley, C. R. (1969). Schizophrenia-like psychoses associated with organic disorders of the central nervous system: A review of the literature. In R. N. Herrington (Ed.). Current problems in neuropsychiatry (pp. 125–147 ).Google Scholar
  23. Ashford Kent: Headley Brothers. Delay, J., Brion, S., and Derouesne, C. (1964). Syndrome de Korsakoff et etiologie tumorale. Revue Neurologique, 111, 97–133.Google Scholar
  24. Direkze, M., Bayliss, S. G., and Cutting, J. C. (1971). Primary tumors of the frontal lobe. British Journal of Clinical Practice, 25, 207–213.PubMedGoogle Scholar
  25. Earle, K. M. (1955). Metastatic brain tumors. Diseases of the Nervous System, 16, 86–93.PubMedGoogle Scholar
  26. Eiser, C. (1980). Effects of chronic illness on intellectual development. Archives of Disease in Children, 55, 766–770.CrossRefGoogle Scholar
  27. Eiser, C., and Lansdown, R. (1977). Retrospective study of intellectual development in children treated for acute lymphoblastic leukemia. Archives of Disease in Children, 52, 525–529.CrossRefGoogle Scholar
  28. Evans, A. E., Gilbert, E. S., and Sandstra, R. (1970). The incidence of central nervous systemGoogle Scholar
  29. leukemia in children. Cancer, 26, 404–410.Google Scholar
  30. Folstein, M. F., Fetting, J. H., Lobo, A., Niaz, U., and Capozzolli, K. D. (1984). Cognitive assessment of cancer patients. Cancer, 31, 2250–2257.Google Scholar
  31. Gaelen, L. H., and Levitan, S. (1967). Solitary intracranial metastasis by Hodgkin’s disease. Archives of Internal Medicine, 120, 740–745.Google Scholar
  32. Geller, W., and Lacher. M. J. (1966). Hodgkin’s disease. Medical Clinics of North America, 50, 819–832.PubMedGoogle Scholar
  33. Gilroy, J., and Meyer, J. S. (1975). Medical neurology ( 2nd ed. ). New York: Macmillan.Google Scholar
  34. Gjerris, F. (1976). Clinical aspects and long-term prognosis of intracranial tumors in infancy and childhood. Developmental Medicine and Child Neurology, 18, 145–159.CrossRefGoogle Scholar
  35. Goff, J. R., Anderson, H. R., Jr., and Cooper, P. F. (1980). Distractibility and memory deficit in longterm survivors of acute lymphoblastic leukemia. Journal of Developmental and Behavioral Pediatrics, 1, 158–161.PubMedCrossRefGoogle Scholar
  36. Golden, C. J. (1981). Diagnosis and rehabilitation in clinical neuropsychology ( 2nd ed. ). Springfield, IL: Charles C Thomas.Google Scholar
  37. Golden, C. J., Moses, J. A., Jr., Coffman, J. A., Miller, W. R., and Strider, F. D. (1983). Clinical neuropsychology: Interface with neurologic and psychiatric disorders. New York: Grune and Stratton.Google Scholar
  38. Halstead, W. C. (1947). Brain and intelligence. Chicago: University of Chicago Press. Harisiadis, L., and Chang, C. H. ( 1977 ). Medulloblastoma in children: A correlation betweenGoogle Scholar
  39. staging and results of treatment. International Journal of Radiation Oncology and Biological Physics,2, 833–841.Google Scholar
  40. Hecaen, H., and Ajuriaguerra, J. (1956). De troubles mentaux au cours des tumeus intracraniennes. Paris: Masson.Google Scholar
  41. Hedley-White, E. T., Smith, B. P., Tyler, H. R., and Peterson, W. P. cephalopathy with remission and five year survival. Journal of Neuropathology and Experimental Neurology, 25, 107–112.Google Scholar
  42. Henson, R. A., Hoffman, H. L., and Urich, H. (1965). Encephalomyelitis with carcinoma. Brain, 88, 449–464.PubMedCrossRefGoogle Scholar
  43. Hirsch, J. F., Reneir, D., Czernichow, R., Benveniste, L., and Pierre-Kahn, A. (1979).Google Scholar
  44. Medullablastoma in childhood. Survival and functional results. Acta Neurochirurgica, 48, 1–15.Google Scholar
  45. Hoppe, R. T., Kushlan, P., and Kaplan, H. S. (1981). The treatment of non-Hodgkin’s lymphoma: A preliminary report of a randomized trial comparing single agent chemotherapy, combination chemotherapy, and whole body irradiation. Blood, 58, 592–598.PubMedGoogle Scholar
  46. Ivnik, R. H., Colligan, R. C., Obetz, S. W., and Smithson, W. A. (1981). Neuropsychologic performance among children in remissions from acute lymphocytic leukemia. Journal of Developmental and Behavioral Pediatrics, 2, 29–34.Google Scholar
  47. Joynt, R. J., and Perret, C. E. (1965). Familial meningiomas. Journal of Neurology, Neurosurgery, and Psychiatry, 28, 163–164.Google Scholar
  48. Kaplan, A. M., and Itabashi, H. H. (1974). Encephalitis associated with carcinoma. Journal of Neurology, Neurosurgery, and Psychiatry, 37, 1166–1172.Google Scholar
  49. Kaufman, G. (1965). Hodgkin’s disease involving the central nervous system. Archives of Neurology, 13, 555–558.PubMedCrossRefGoogle Scholar
  50. Keschner, M., Bender, M. B., and Strauss, I. (1936). Mental symptoms in cases of tumor of the temporal lobe. Archives of Neurology and Psychiatry, 110, 572–596.CrossRefGoogle Scholar
  51. Keschner, M., Bender, M. B., and Strauss, I. (1938a). Mental symptoms in cases of subtentorial tumor. Archives of Neurology and Psychiatry, 37, 1–15.CrossRefGoogle Scholar
  52. Keschner, M., Bender, M. B., and Strauss, I. (1938b). Mental symptoms associated with brain tumor: A study of 530 verified cases. Journal of the American Medical Association, 110, 714–718.CrossRefGoogle Scholar
  53. Kimura, D. (1967). Right temporal lobe damage: Perception of unfamiliar stimuli after damage. Archives of Neurology, 8, 264–271.Google Scholar
  54. Knights, R. M. (1980). Revised smoothed normative data on the neuropsychological test battery for children. Unpublished manuscript.Google Scholar
  55. Koocher, G. P. (1973). Childhood, death, and cognitive development. Developmental Psychology, 9, 369–375.CrossRefGoogle Scholar
  56. Kramer, S., and Lee, K. F. (1974). Complications of radiation therapy: The central nervous system. Seminars of Roentgentology, 9, 75–83.Google Scholar
  57. Kun, L. E., Mulhern, R. K., and Crisco, J. J. (1983). Quality of life in children treated for brain tumors: Intellectual, emotional and academic function. Journal of Neurosurgery, 58, 1–6.Google Scholar
  58. Lishman, W. (1978). Organic psychiatry: The psychological consequences of cerebral disorder.Google Scholar
  59. Luria, A. R. (1966). Higher cortical functions in man. New York: Basic Books.Google Scholar
  60. Martin, J. B., and Banker, B. Q. (1969). Subacute multifocal leukoencephalopathy with widespread intranuclear inclusions. Archives of Neurology, 21, 590–595.Google Scholar
  61. Mauer, A. E. (1980). Therapy of acute lymphocytic leukemia in childhood. Blood, 56, 1–10.PubMedGoogle Scholar
  62. McCormick, W. F., Menezes, A. H., and Gin, O. I. (1972). Meningioma occurring in a patient treated for medulloblastoma. Journal of the Iowa Medical Society, 62, 67–71.Google Scholar
  63. Meier, M. J., and French, L. A. (1965). Lateralized deficits in complex visual discrimination and bilateral transfer of reminiscence following unilateral temporal lobotomy. Neuropsychologia, 3, 261–272.CrossRefGoogle Scholar
  64. Milner, B. (1963). Effects of different brain lesions on card sorting. Archives of Neurology, 9, 90.CrossRefGoogle Scholar
  65. Milner, B. (1971). Interhemispheric differences in the localization of psychological processes in man. British Medical Bulletin, 27, 272.PubMedGoogle Scholar
  66. Moehle, K. A., Berg, R. A., Ch’ien, L. T., and Lancaster, W. (1983). Language-related skills in children with acute lymphocytic leukemia. Journal of Developmental and Behavioral Pediatrics, 4, 257–261.PubMedGoogle Scholar
  67. Morton, D. L., Itaboshi, H. H., and Grimes, O. F. (1966). Nonmetastatic neurologic complications of bronchogenic carcinoma: The carcinomatous neuromyopathies. Journal of Thoracic and Cardiovascular Surgery, 51, 14–29.Google Scholar
  68. Moss, H. A., Nannis, E. D., and Poplack, D. G. (1981). The effects of prophylactic treatment of the central nervous system on the intellectual functioning of children with acute lymphocytic leukemia. American Journal of Medicine, 71, 47–52.CrossRefGoogle Scholar
  69. Mulhern, R. K., Crisco, J. J., and Kun, L. E. (1983). Neuropsychological sequelae of childhood brain tumors: A review. Journal of Clinical Child Psychology, 12, 66–73.Google Scholar
  70. Obetz, S. W., Ivnik, R. J., Smithson, W. A., Colligan, R. C., Groover, R. V., Gilchrist, G. J., Houser, D. W., Burgert, F. O., and Klass, D. W. (1979). Neuropsychological follow-up study of children with acute lymphocytic leukemia: A preliminary report. American Journal of Pediatric Hematology/Oncology, 1, 207–213.Google Scholar
  71. Oxman, T. E., and Silberfarb, P. M. (1980). Serial cognitive testing in cancer patients receiving chemotherapy. American Journal of Psychiatry, 137, 1263–1265.Google Scholar
  72. Perret, E. (1974). The left frontal lobe of man and the suppression of habitual responses in verbal categorical behavior. Neuropsychologia, 12, 323–330.PubMedCrossRefGoogle Scholar
  73. Portlock, C. S. (1980). Management of the indolent non-Hodgkins’ lymphomas. Seminars in Hematology, 7, 292–301.Google Scholar
  74. Raimondi, A. J., and Tomita, T. (1979). Advantages of total resection of medullablastoma and disadvantages of full head post-operative radiation therapy. Child’s Brain, 5, 550–551.Google Scholar
  75. Robbins, S. L. (1974). Pathologic basis of disease. Philadelphia: Saunders.Google Scholar
  76. Roland, P. E. (1976). Astereognosis. Archives of Neurology, 33, 543–550.CrossRefGoogle Scholar
  77. Russell, R. W. R., and Pennybacker, J. B. (1961). Craniopharyngioma in the elderly. Journal of Neurology, Neurosurgery, and Psychiatry, 24, 1–13.Google Scholar
  78. St. James-Roberts, I. (1979). Neurological plasticity, recovery from brain insult and child development. In H. W. Reese (Ed.), Advances in child development and behavior (Vol. 14, pp. 113–133 ). New York: Academic Press.Google Scholar
  79. Satz, P., and Fletcher, J. M. (1981). Emergent trends in neuropsychology: An overview. Journal of Consulting and Clinical Psychology, 49, 851–865.PubMedCrossRefGoogle Scholar
  80. Schlesinger, B. (1950). Mental changes in intracranial tumors and related problems. Confina Neurologia, 10, 225–263.CrossRefGoogle Scholar
  81. Scoville, W. B., and Milner, B. (1957). Loss of recent memory after bilateral hippocampal lesions. Journal of Neurology, Neurosurgery, and Psychiatry, 20, 21–22.CrossRefGoogle Scholar
  82. Selecki, B. R. (1964). Cerebral mid-line tumors involving the corpus callosum among mental hospital patients. Medical Journal of Australia, 2, 954–960.Google Scholar
  83. Silverman, C. L., Thomas, P. R., Palkes, H., Kovnar, E., Talent, B., and Bedwinek, J. M. (1982). Late psychological and intellectual effects on patients and their families following definitive radiotherapy for childhood medullablastoma. American Society of Clinical Oncology Abstracts, 23, 49.Google Scholar
  84. Sohn, D., Valensi, Q., and Miller, S. P. (1967). Neurologic manifestations of Hodgkin’s disease. Archives of Neurology, 17, 429–436.CrossRefGoogle Scholar
  85. Spunberg, J. J., Chang, C. H., Goldman, M., Auricchio, E., and Bell, J. (1981). Quality of long-term survival following irradiation for intracranial tumors in children under the age of two. International Journal of Radiation Oncology and Biological Physics, 7, 727–736.CrossRefGoogle Scholar
  86. Stehbens, J. A., Kisker, C. T., and Wilson, B. K. (1983). Achievement and intelligence test-retest performance in pediatric cancer patients at diagnosis and one year later. Journal of Pediatric Psychology, 8, 47–56.PubMedCrossRefGoogle Scholar
  87. Strauss, I., and Keschner, M. (1935). Mental symptoms in cases of tumor in the frontal lobe. Archives of Neurology and Psychiatry, 33, 986–1007.CrossRefGoogle Scholar
  88. Strobos, R. R. J. (1953). Tumors of the temporal lobe. Neurology, 3, 752–760.PubMedCrossRefGoogle Scholar
  89. Sullivan, M. P. (1957). Intracranial complications of leukemia in children. Pediatrics, 20, 757785.Google Scholar
  90. Tamaroff, M., Salwen, R., Allen, J., Murphy, M., and Nir, Y. (1982). Neuropsychological test performance in children treated for malignant tumors of the posterior fossa. American Society of Clinical Oncology Abstracts, 23, 50.Google Scholar
  91. Teuber, H. L. (1964). The riddle of frontal lobe function in man. In J. M. Warren and K. Akert (Eds.), The frontal granular cortex and behavior (pp. 75–97 ). New York: McGraw-Hill.Google Scholar
  92. Ultmann, J. E., and Jacobs, R. H. (1985). The non-Hodgkin’s lymphomas. Ca-A Cancer Journal for Clinicians, 35, 66–87.PubMedCrossRefGoogle Scholar
  93. Walton, J. N. (Ed.). (1977). Brain’s diseases of the nervous system ( 8th ed. ). New York: Oxford University Press.Google Scholar
  94. Ward, D. W., Mattison, M. C., and Fian, R. (1973). Association between previous tuberculous infection and cerebral glioma. British Medical Journal, 1, 83–84.Google Scholar
  95. Wells, C. E., and Silver. R. T. (1967). Neurologic manifestations of the acute leukemias: Clinical study. Annals of Internal Medicine, 46, 439–449.Google Scholar
  96. Wilkinson, P. C. (1964). Serological findings in carcinomatous neuromyopathy. Lancet, 1, 1301–1303.PubMedCrossRefGoogle Scholar
  97. Wilkinson, P. C., and Zeromski, J. (1965). Immunofluorescent detection of antibodies against neurons in sensory carcinomatous neuropathy. Brain, 88, 529–538.PubMedCrossRefGoogle Scholar
  98. Young, J. L., Percy, C. L., Asire, A. J., Berg, J. W., Cusano, M. M., Gloecker, L. A., Horm, J. W., Laurie, W. I., Pollack, E. S., and Shambaugh, E. M. (1982). Cancer incidence and mortality in the United States, 1973–1977 (Monograph No. 57 ). Washington, DC: National Cancer Institute.Google Scholar

Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Richard A. Berg
    • 1
  1. 1.Department of Behavioral Medicine and PsychiatryWest Virginia University Medical CenterCharlestonUSA

Personalised recommendations