The Chemical Hazard of Anti-Implantation Assessed and Analyzed Both In Vitro and In Vivo

  • D. Michael Pugh
  • Hector S. Sumano


I was tempted to offer this paper for several reasons. The term hazard describes the nature of something undesirable which may happen to an individual or population while the term risk describes the probability that the hazard will happen. Plainly identification of the hazard has to precede the assessment of risk. My paper describes a novel in vitro technique for the demonstration of and quantitation of the hazard of oestrogenicity using the maturation and implantation of the developing mouse embyro.


Chemical Hazard Mouse Blastocyst Post Coitum Tubal Transport Genicity Risk Assessment 
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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • D. Michael Pugh
    • 1
  • Hector S. Sumano
    • 1
  1. 1.Department of Medicine and Pharmacology Faculty of Veterinary MedicineUniversity College DublinBallsbridge, Dublin 4Republic of Ireland

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