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DNA Fragmentation and Sister Chromatid Exchanges Induced by Commercial Auramine O, Purified Auramine, and Michler’s Ketone

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Abstract

In IARC monograph No. 1 (IARC monograph, 1972) Auramine O is reported to be widely used in industry. An high increase in bladder tumors in workers engaged in the manufacture of Auramine was reported (Case and Pearson, 1954). A recent study (Report of a IARC Working Group, 1980) evaluated the data on human and experimental animal carcinogenesis. Auramine was classified in group 2, probably carcinogenetic for humans, subgroup B, lower degree of evidence.

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© 1983 Springer Science+Business Media New York

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Vecchio, D. et al. (1983). DNA Fragmentation and Sister Chromatid Exchanges Induced by Commercial Auramine O, Purified Auramine, and Michler’s Ketone. In: Castellani, A. (eds) The Use of Human Cells for the Evaluation of Risk from Physical and Chemical Agents. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1117-2_43

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  • DOI: https://doi.org/10.1007/978-1-4757-1117-2_43

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1119-6

  • Online ISBN: 978-1-4757-1117-2

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