Assessment of Human Lymphoid Cell Damage Induced by Therapeutic Levels of 8-Methoxypsoralen and Long Wavelength Ultraviolet Radiation In Vitro

  • Kenneth H. Kraemer


An earlier presentation to this conference dealt with general properties of human lymphoblastoic cell lines and their possible role in risk assessment. This paper will present a specific example of the use of lymphoblastoid cell lines to evaluate risk in patients receiving oral 8-methoxypsoralen (8-MOP) plus longwave ultraviolet radiation (UV-A) photochemotherapy. This experimental therapy has been given the acronym “PUVA.”


Lymphoblastoid Cell Line Mycosis Fungoides Surface Dose Total Blood Volume Human Lymphoblastoid Cell 
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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Kenneth H. Kraemer
    • 1
  1. 1.Laboratory of Molecular CarcinogenesisNational Cancer InstituteBethesdaUSA

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