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Machinery of the Mind pp 115–139Cite as

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Cellular and Network Mechanisms in the Kindling Model of Epilepsy: The Role of GABAergic Inhibition and the Emergence of Strange Attractors

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Abstract

The kindling model of epilepsy offers the possibility of studying a number of general properties of the central nervous system: namely, (1) how plasticity or malleability in neuronal networks can be expressed and (2) how the system may become instable such that the ongoing activity is disrupted. The first point pertains to the question of synaptic plasticity, and the second point is related to the question of the maintenance or interruption of the flow of consciousness.

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Authors
  1. Fernando H. Lopes Da Silva
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  2. Willem Kamphuis
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  3. Jan M. A. M. Van Neerven
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  4. Jan Pieter M. Pijn
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Editors and Affiliations

  1. Brain Research Laboratories, New York University Medical Center, 10020, New York, New York, USA

    E. Roy John M.D.  & Leslie S. Prichep  & 

  2. National University of Mexico, Ciudad de Los Deportes, Mexico

    Thalia Harmony

  3. Centro Nacional de Investigaciones Cientifícas Ciudad de la Habana, Cuba

    Mitchell Valdés-Sosa  & Pedro A. Valdés-Sosa  & 

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Da Silva, F.H.L., Kamphuis, W., Van Neerven, J.M.A.M., Pijn, J.P.M. (1990). Cellular and Network Mechanisms in the Kindling Model of Epilepsy: The Role of GABAergic Inhibition and the Emergence of Strange Attractors. In: John, E.R., Harmony, T., Prichep, L.S., Valdés-Sosa, M., Valdés-Sosa, P.A. (eds) Machinery of the Mind. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4757-1083-0_6

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  • DOI: https://doi.org/10.1007/978-1-4757-1083-0_6

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