Kinins—II pp 569-576 | Cite as

Improvement of Glucose Assimilation and Protein Degradation by Bradykinin in Maturity Onset Diabetics and in Surgical Patients

  • Matthias Wickimayr
  • Gunther Dietze
  • Bernulf Gunther
  • Ingolf Bottger
  • Lothar Mayer
  • Peter Janetschek
Part of the Advances in Experimental Medicine and Biology book series (AEMB)


Impaired glucose assimilation and accelerated protein degradation are concomitant symptoms of insulin deficiency as in diabetes and also of reduced insulin sensitivity as during postoperative stress. Since it is known that kininogen levels are reduced in traumatic stress (1) and that kinin liberation is involved in the peripheral action of insulin (2,3), the influence of kinin infusion on carbohydrate tolerance and urinary nitrogen excretion was investigated in normal and diabetic subjects and in surgical patients.


Surgical Patient Blood Glucose Concentration Intravenous Glucose Tolerance Test Reduce Insulin Sensitivity Glucose Injection 
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Copyright information

© Springer Science+Business Media New York 1979

Authors and Affiliations

  • Matthias Wickimayr
    • 1
  • Gunther Dietze
    • 1
  • Bernulf Gunther
    • 1
  • Ingolf Bottger
    • 1
  • Lothar Mayer
    • 1
  • Peter Janetschek
    • 1
  1. 1.Abteilung fur Stoffwechsel und Endokrinologie des Akademischen Lehrkrankenhauses Munchen-SchwabingMunchen 40GFR

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