Abstract
Previously we have reported on the influence of the kallikreinkinin system on the active transport of amino acids and glucose across the rat small intestines (Moriwaki and Fukimori, 1975; Moriwaki et al., 1977) and the effect of kinin on accumulation of valine into the intestinal segment (Moriwaki et al., 1977). It has been recognized that some amino acids or glucose are co-transported with Na in the small intestines (Crane, 1965; Rosenberg et al., 1965). It is a well-known fact that an active solute transport is associated with an increase in transmural potential difference (PDt) of the small intestines (Barry et al., 1964; Schultz and Zalusky, 1964; Lyon and Crane, 1966; Hoshi and Komatsu, 1968). Meanwhile, Okada et al. (1977b) has demonstrated that the resistance of the intestines was not altered by the addition of glucose and glycine in the mucosal fluid. Therefore, the enhancement of absorption of glucose and amino acids in the intestines seems to be the result of the stimulation of Na+ flux in the absorptive cells by the kinins.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Barry, R.J,C., S. Dickstein, J. Matthews, D.H. Smyth and E.M. Wright 1964. Electrical potentials associated with intestinal sugar transport, J. Physiol. (London). 171: 316.
Crane, R.K., 1965, Nat-dependent transport in the intestine and other animal tissue, Fed. Proc. 24, 1000.
Dennhardt, D. and Í.J. Haberich, 1973, Effect of kallikrein on the absorption of water, electrolytes, and hexoses in the intestine of rats, in: Kininogenases, eds. G.L. Haberland and J.W. Rohen (F.K. Schattauer Verlu’3tuttgart,0ew York) p. 81.
Hoshi, T. and Y. KomĂĽtoo, I968, Sugar-evoked potential in isolated toad intestine, J9o. J. Physiol. 18, 508.
Lyon, I. and R.K. Crane, 1966, Studies on transmural potentials in vitro in relation to intestinal absorption. I. Apparent Michaelis constants for Nat dependent sugar transport, Bincbim. Biophys. Acta 112, 278.
Moriwaki, C. and H. Fujimori, 1975, Further observations on the influence of the kallikrein-kinin system on the intestinal absorption, in: Kininogenases 3, eds. G.L. Haberland, J.W. Rohen, C. Bl8bel and P. Huber (F.K. Schattauer VerIag Stottgart’ New York) p. 57.
Moriwaki, C., B. Fujimori, H. Moriya and K. Kizuki, 1977, Studies on kallikrein. IV. Enhancement of valine transport across the rat small intestine, Chem. Pharm. Bull. 25, 1174.
Moriwaki, C., B. Fujimori and Y. Toyono, 1977, Intestinal kallikrein and the influence of kinin on the intestinal transport, in Kininogenases 4, eds. G.L. Babezlaud, J.W. Rohen and T. Suzuki ( F.K. Schattauer Verlag. Stuttgart, New York ) p. 283.
Okada, Y., W.Tsuchiya, A. Irimajiri and A. Inouye, I977e` Electrical properties and active solute transport in rat small intestine I. Potential profile changes associated with sugar and amino acid transports, J. Membrane Biol. 31, 205
Okada, Y., A. Irimajiri and A. Inouye, 1977b, Electrical properties and active solute transport in rat small intestine II. Conductive properties of transepithelial routes, J. l~eH.zaoe Biol. 31, 221.
Rosenberg, I.B., A.L. Coleman and L.E. Roaeobcg, 1965, The role of sodium ion in the transport of amino acids by the intestine, Biochim. Biophys. Acta 102, 161
Rose, R.C. and S.G. Schultz, 1971, Studies on the electrical potential profile across rabbit ileum. Effects of sugars and amino acids on transmural and transmucosal electrical potential differences, J. Gen. Pbyaiol, 57, 639
Schultz, S.G., R.A. Frizzell and H.N. Nellans, 1974, Ion transport by mammalian small intestine, Annu. Rev. Physiol. 36, 51.
Schultz, S.G. and R. Zalusky, 1964, Ion transport in isolated rabbit ileum zz. The interaction between active sodium and sugar transport, J. Gen, Physiol. 47, 1043.
White, J.ĂŤ. and W. McD. Armstrong, 197I, Effect of transported solutes on membrane potentials in bullfrog small intestine, 4m. J. Physiol. 221, 194.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Springer Science+Business Media New York
About this chapter
Cite this chapter
Moriwaki, C., Fujimori, H. (1979). Effect of Kallikrein-Kinin System on Ion Transport Across Rat Small Intestine. In: Fujii, S., Moriya, H., Suzuki, T. (eds) Kinins—II. Advances in Experimental Medicine and Biology, vol 120. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-0926-1_42
Download citation
DOI: https://doi.org/10.1007/978-1-4757-0926-1_42
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4757-0928-5
Online ISBN: 978-1-4757-0926-1
eBook Packages: Springer Book Archive