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Molecular Biology of Membrane-Bound Complexes in Phototrophic Bacteria pp 479–487Cite as

The Structure of Porin from Rhodobacter capsulatus at 6 Å

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Abstract

Porins are a class of integral membrane proteins which confer well-defined permeability properties to the outer membrane of gram-negative bacteria. They form aqueous channels across the outer membrane which allow the passage of small polar molecules up to an exclusion size of, typically, 600 daltons. For recent reviews see [1, 2, 3]. The geometry of the channel and the distribution of the amino acid side chains which form its surface, determine the individual characteristics of porins : the exclusion limit as well as the selectivity as e.g. for anions, cations, phosphates or sugars[3, 4]. Except for this selectivity the solutes seem to pass the channel by free diffusion. The exclusion limit is large enough to allow for the passage of antibiotics[5].

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Author information

Authors and Affiliations

  1. Institut für Biophysik und Strahlenbiologie, Albertstr. 23, 7800, Freiburg i.Br., Germany

    W. Welte, T. Wacker & U. Nestel

  2. Institut für Biologie II, Mikrobiologie, Schänzlestr. 1, 7800, Freiburg i.Br., Germany

    D. Woitzik & J. Weckesser

  3. Institut für Organische Chemie und Biochemie, Albertstr. 21, 7800, Freiburg i.Br., Germany

    M. S. Weiss & G. E. Schulz

Authors
  1. W. Welte
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  2. T. Wacker
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  3. U. Nestel
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  4. D. Woitzik
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  5. J. Weckesser
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  6. M. S. Weiss
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  7. G. E. Schulz
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Editor information

Editors and Affiliations

  1. Albert-Ludwigs University, Freiburg, Federal Republic of Germany

    Gerhart Drews

  2. University of Hull, Hull, UK

    Edwin A. Dawes

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© 1990 Springer Science+Business Media New York

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Welte, W. et al. (1990). The Structure of Porin from Rhodobacter capsulatus at 6 Å. In: Drews, G., Dawes, E.A. (eds) Molecular Biology of Membrane-Bound Complexes in Phototrophic Bacteria. FEMS Symposium. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0893-6_56

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  • DOI: https://doi.org/10.1007/978-1-4757-0893-6_56

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0895-0

  • Online ISBN: 978-1-4757-0893-6

  • eBook Packages: Springer Book Archive

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