Signal Transduction of Sperm-Egg Interaction Causing Periodic Calcium Transients in Hamster Eggs

  • Shun-ichi Miyazaki


The study of fertilization or egg activation has a long history, over a century, and experiments have been done mainly using sea urchin gametes, as shown in this book. The study of mammals was much delayed because of the difficulty in maintaining and fertilizing the gametes in vitro. In these last 30 years, these problems have been overcome through advances in cell culture techniques, and extensive studies have now been completed on mammalian fertilization, based on microscopic and morphological observations. However, because of the limitation in the number of collectable eggs, some difficulties still remain for further studies based on techniques such as biochemical analysis.


Inositol Trisphosphate Fertilization Potential Flagellar Motion Constant Current Pulse Hyperpolarizing Response 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Shun-ichi Miyazaki
    • 1
  1. 1.Department of PhysiologyTokyo Women’s Medical CollegeKawada-cho, Shinjuku-ku, Tokyo, 162Japan

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