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Reproductive Cyclicity and Breeding in the Squirrel Monkey

  • W. Richard Dukelow
Chapter

Abstract

Some behavioral research was done with squirrel monkeys in a captive environment in the 1930s, but the first captive births of this species did not occur until 1940, and only more recently has extensive use been made of it. Its value in various nutritional and cardiovascular studies has led to increased efforts to breed this animal in captivity. Its small size, ease of handling, and relatively simple management requirements make it an attractive animal for research laboratories, and in fact it is the second most commonly used species for the purpose.

Keywords

Nonhuman Primate Corpus Luteum Estrous Cycle Squirrel Monkey Artificial Insemination 
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References

  1. Ariga, S., and Dukelow, W. R., 1977a, Non-surgical (laparoscopic) uterine flushing and egg recovery techniques in the squirrel monkey (Saimiri sciureus), Primates 18 (2): 453–457.CrossRefGoogle Scholar
  2. Ariga, S., and Dukelow, W. R., 1977b, Recovery of preimplantation blastocysts in the squirrel monkey by a laparoscopic technique, Fertil. Steril. 28 (5): 577–580.Google Scholar
  3. Ariga, S., Dukelow, W. R., Emley, G. S., and Hutchinson, R. R., 1978, Possible errors in identification of squirrel monkeys (Saimiri sciureus) from different South American points of export, J. Med. Primato7: 129–135.Google Scholar
  4. Asakawa, T., and Dukelow, W. R., 1982, Chromosomal analyses after in vitro fertilization of squirrel monkey (Saimiri sciureus) oocytes, Biol. Reprod. 26: 579–583.CrossRefGoogle Scholar
  5. Asakawa, T., Chan, P. J., and Dukelow, W. R., 1982, Time sequence of in vitro maturation and chromosomal normality in metaphase I and metaphase II of the squirrel monkey (Saimiri sciureus) oocyte, Biol. Reprod. 27: 118–124.CrossRefGoogle Scholar
  6. Baker, C. A., and Hendrickx, A. G., 1977, The number of umbilical vessels in the squirrel monkey (Saimiri sciureus), Folia Primato 27: 230–233.CrossRefGoogle Scholar
  7. Baldwin, J. D., and Baldwin, J. I., 1971, Squirrel monkeys (Saimiri) in natural habitats in Panama, Columbia, Brazil and Peru, Primates 12: 45–61.CrossRefGoogle Scholar
  8. Bantin, G. C., 1969, Reproduction in the squirrel monkey (Saimiri sciureus), J. Inst. Anim. Tech. 20 (3): 83–90.Google Scholar
  9. Barry, J., 1979, Immunofluorescence study of the preoptico-terminal LRH tract in the female squirrel monkey during the estrous cycle, Cell Tissue Res. 198: 1–13.PubMedCrossRefGoogle Scholar
  10. Barry, J., and Croix, D., 1978, Immunofluorescence study of the hypothalamoinfundibular LRH tract and serum gonadotropin levels in the female squirrel monkey during the estrous cycle, Cell Tissue Res. 192: 215–226.PubMedCrossRefGoogle Scholar
  11. Beischer, D. E., and Furry, D. E., 1964, Saimiri sciureus as an experimental animal, Anat. Rec. 148: 615–624.Google Scholar
  12. Benirschke, K., and Miller, C. J., 1982, Anatomical and functional differences in the placenta of primates, Biol. Reprod. 26: 29–53.CrossRefGoogle Scholar
  13. Bennett, J. P., 1967a, Semen collection in the squirrel monkey, J. Reprod. Fertil. 13: 353–355.PubMedCrossRefGoogle Scholar
  14. Bennett, J. P., 1967b, Artificial insemination of the squirrel monkey J. Endocrinal. 37: 473–474.CrossRefGoogle Scholar
  15. Bennett, J. P., 1967c, The induction of ovulation in the squirrel monkey (Saimiri sciureus) with pregnant mares serum (PMS) and human chorionic gonadotrophin (HCG), J. Reprod. Fertil. 13: 357–359.PubMedCrossRefGoogle Scholar
  16. Brown, G. M., Grota, L. J., Penney, D. P., and Reichlin, S., 1970, Pituitary–adrenal function in the squirrel monkey, Endocrinology 86: 519–529.PubMedCrossRefGoogle Scholar
  17. Butler, H., 1974, Evolutionary trends in primate sex cycles, in: Contributions to Primatology, Volume 3 ( H. Kuhn, ed.), S. Karger, Basel, pp. 2–35.Google Scholar
  18. Chan, P. J., Hutz, R. J., and Dukelow, W. R., 1982, Nonhuman primate in vitro fertilization: Seasonality cumulus cells, cyclic nucleotides, ribonucleic acid and viability assays, Fertil. Steril. 38: 609–615.Google Scholar
  19. Clewe, T. H., 1969, Observations on reproduction of squirrel monkeys in captivity, J. Reprod. Fertil. 6 (Suppl.): 151–156.Google Scholar
  20. Cline, E. M., 1972, Investigations on in vitro fertilization for three mammalian species: Golden hamster, squirrel monkey and New Zealand White rabbit, M. S. Thesis, Department of Biochemistry, University of Georgia, Athens, Georgia.Google Scholar
  21. Cline, E. M., Gould, K. G., and Foley, C. W., 1972, Regulation of ovulation, recovery of mature ova and fertilization in vitro of mature ova of the squirrel monkey (Saimiri sciureus), Fed. Proc. 31: 177.Google Scholar
  22. Coe, C. L., and Levine, S., 1981, Psychoendocrine relationships underlying reproductive behavior in the squirrel monkey, Int. J. Ment. Health 10 (2–3): 22–42.Google Scholar
  23. DeMayo, F. J., 1983, Cryopreservation and xenogenous fertilization of hamster and squirrel monkey ova, Proc. Mich. Acad. Sci., p. 14.Google Scholar
  24. DeMayo, F. J., Mizoguchi, H., and Dukelow, W. R., 1980, Fertilization of squirrel monkey and hamster ova in the rabbit oviduct (Xenogenous fertilization), Science 208: 1468–1469.PubMedCrossRefGoogle Scholar
  25. Denis, L. T., Poindexter, A. N., Ritter, M. B., Seager, S. W. J., and Deter, R. L., 1976, Freeze preservation of squirrel monkey sperm for use in timed fertilization studies, Fertil. Steril. 27: 723–729.Google Scholar
  26. Denniston, R. H., 1963, Notes on the vaginal cornification cycle of captive squirrel monkeys, J. Mammal. 45: 471.CrossRefGoogle Scholar
  27. Dukelow, W. R., 1970, Induction and timing of single and multiple ovulations in the squirrel monkey (Saimiri sciureus), J. Reprod. Fertil. 22: 303–309.PubMedCrossRefGoogle Scholar
  28. Dukelow, W. R., 1978a, Reproduction in the squirrel monkey (Saimiri sciureus), Rec. Adv. Primatol. 2: 195–200.Google Scholar
  29. Dukelow, W. R., 1978b, Laparoscopic research techniques in mammalian embryology, in: Methods in Mammalian Reproduction ( J. C. Daniel, ed.), pp. 247–271, Academic Press, New York.Google Scholar
  30. Dukelow, W. R., 1979, Human chorionic gonadotropin: Induction of ovulation in the squirrel monkey (Saimiri sciureus), Science 206: 234.PubMedCrossRefGoogle Scholar
  31. Dukelow, W. R., 1982, The squirrel monkey, in: Universities Federation for Animal Welfare Handbook ( J. Remfry, ed.), MTP Press, London.Google Scholar
  32. Dukelow, W. R., 1983, Ovum recovery and embryo transfer in primates, in: Mammalian Egg Transfer ( C. E. Adams, ed.), CRC Press, Boca Raton, Florida, pp. 155–174.Google Scholar
  33. Dukelow, W. R., and Ariga, S., 1976, Laparoscopic techniques for biomedical research, J. Med. Primato5: 82–99.Google Scholar
  34. Dukelow, W. R., and Kuehl, T. J., 1975, In vitro fertilization of non human primates, in: Proc. 4th Eur. Congr. Fertil. Steril. — Extrait de la fecondation: Colloque de la societé nationale pour l’étude de la sterilité et de la fecondité, Masson, Paris, pp. 67–80.Google Scholar
  35. Dukelow, W. R., Jewett, D. A., and Rawson, J. M. R., 1973, Follicular development and ovulation in Macaca fascicularis, Saimiri sciureus and Galago senegalensis, Am. J. Phys. Anthropol. 38: 207–210.PubMedCrossRefGoogle Scholar
  36. Dukelow, W. R., Theodoran, C. G., Howe-Baughman, J., and Magee, W. T., 1981, Ovulatory patterns in the squirrel monkey (Saimiri sciureus), Anim. Reprod. Sci. 4: 55–63.CrossRefGoogle Scholar
  37. DuMond, F. V., and Hutchinson, T. C., 1967, Squirrel monkey reproduction: The “fatted” male phenomenon and seasonal spermatogenesis, Science 158: 1067–1070.CrossRefGoogle Scholar
  38. DuMond, F. V., 1968, The squirrel monkey in a seminatural environment, in: The Squirrel Monkey ( L. A. Rosenblum and R. W. Cooper, eds.), Academic Press, New York, pp. 87–145.Google Scholar
  39. Fujimoto, S., Pahlavan, N., and Dukelow, W. R., 1974, Chromosome abnormalities in rabbit preimplantation blastocysts induced by superovulation, J. Reprod. Fertil. 38: 97–103.PubMedCrossRefGoogle Scholar
  40. Ghosh, M., Hutz, R. J., and Dukelow, W. R., 1982, Serum estradiol 1713, progesterone and relative LH levels in Saimiri sciureus: Cyclic variations and the effect of laparoscopy and follicular aspiration, J. Med. Primato11: 312–318.Google Scholar
  41. Goss, C. M., Popjoy, L. T., Fusiler, J. L., and Smith, T. M., 1968, Observations on the relationship between embryological development, time of conception and gestation, in: The Squirrel Monkey ( L. A. Rosenblum and R. W. Cooper, eds.), pp. 171–192, Academic Press, New York.Google Scholar
  42. Gould, K. G., Cline, E. M., and Williams, W. L., 1973, Observations on the induction of ovulation and fertilization in vitro in the squirrel monkey (Saimiri sciureus), Fertil. Steril. 24 (41:260–268).Google Scholar
  43. Graham, C. E., 1969a, Glycogen and glycogen-metabolizing enzymes in the squirrel monkey uterine cervix, Am. J. Obstet. Gynecol. 102 (7): 989–996.Google Scholar
  44. Graham, C. E., 1969b, Estrogen-induced changes at the cervical squamocolumnar junction of the squirrel monkey, Am. J. Obstet. Gynecol. 104 (6): 839–845.PubMedGoogle Scholar
  45. Graham, C. E., and Bradley, C. F., 1971, Polyovular follicles in squirrel monkeys after prolonged diethylstilboestrol treatment, J. Reprod. Fertil. 27: 181–185.PubMedCrossRefGoogle Scholar
  46. Graham, C. E., and Manocha, S. L., 1971, The effect of chronic estrogenic stimulation on the squirrel monkey cervical epithelium, Virchows Arch. Abt. B. Zellpathol. 7: 147–156.Google Scholar
  47. Harrison, R. M., and Dukelow, W. R., 1971, Megestrol acetate: Its effect on the inhibition of ovulation in squirrel monkeys, Saimiri sciureus, J. Reprod. Fertil. 25: 99–101.PubMedCrossRefGoogle Scholar
  48. Harrison, R. M., and Dukelow, W. R., 1973, Seasonal adaption of laboratory-maintained squirrel monkeys (Saimiri sciureus), J. Med. Primatol. 2: 277–283.PubMedGoogle Scholar
  49. Harrison, R. M., and Dukelow, W. R., 1974, Morphological changes in the Saimiri sciureus ovarian follicles as detected by laparoscopy, Primates 15 (4): 305–309.CrossRefGoogle Scholar
  50. Harrison, R. M., Rawson, J. M. R., and Dukelow, W. R., 1974, Megestrol acetate. II. Effects on ovulation in nonhuman primates as determined by laparoscopy, Fertil. Steril. 25 (1): 51–56.Google Scholar
  51. Hodgen, G. D., Stolzenberg, S. J., Jones, D. C. L., Hildebrand, D. F., and Turner, C. K., 1978, Pregnancy diagnosis in squirrel monkeys: Hemagglutination test, radioimmunoassay, and bioassay of chorionic gonadotropin, J. Med. Primato7: 59–64.Google Scholar
  52. Hopf, S., 1967, Notes on pregnancy, delivery, and infant survival in captive squirrel monkeys, Primates 8: 323–332.CrossRefGoogle Scholar
  53. Hupp, E. W., 1972, Husbandry procedures in an indoor breeding squirrel monkey colony, in: Medical Primatology ( E. I. Goldsmith and J. Moor-Jankowski, eds.), Karger, Basel, Part I, pp. 100–104.Google Scholar
  54. Hutchinson, T. C., 1970, Vaginal cytology and reproduction in the squirrel monkey (Saimiri sciureus), Folio Primato12: 212–223.CrossRefGoogle Scholar
  55. Hutz, R. J., Ghosh, M., Dukelow, W. R., 1984, Steroid uptake and 3H-uridine incorporation by early hamster and squirrel monkey (in vitro fertilized) embryos: Effects of ovulatory regimen, Zool. Sci., 1: 771–776.Google Scholar
  56. Jarosz, S. J., Kuehl, T. J., and Dukelow, W. R., 1977, Vaginal cytology, induced ovulation and gestation in the squirrel monkey (Saimiri sciureus), Biol. Reprod. 16: 97–103.CrossRefGoogle Scholar
  57. Johnson, M. J., Harrison, R. M., and Dukelow, W. R., 1972, Studies on oviductal fluid and in vitro fertilization in rabbits and nonhuman primates, Fed. Proc 31: 278.Google Scholar
  58. Jones, T. C., Thorington, R. W., Hu, M. M., Adams, E., and Cooper, R. W., 1973, Karyotypes of squirrel monkeys (Saimiri sciureus) from different geographical regions, Am. J. Phys. Anthropol. 38: 269–277.PubMedCrossRefGoogle Scholar
  59. Kaack, B., Walker, L., and Brizzee, K. R., 1979, The growth and development of the squirrel monkey (Saimiri sciureus) Growth 43: 116–135.PubMedGoogle Scholar
  60. Kaplan, J. N., 1977, Breeding and rearing squirrel monkeys (Saimiri sciureus) in captivity, Lab. Anim. Sci. 27: 557–567.Google Scholar
  61. Kaplan, J. N., Chen, J., Smith, E., and Davidson, J., 1981, The development of seasonal variation in gonadal hormones and body weight in the maturing squirrel monkey, Int. J. Primato!. 2: 369380.Google Scholar
  62. Kerber, W. T., Conaway, C. H., and Moore Smith, D., 1977, The duration of gestation in the squirrel monkey (Saimiri sciureus), Lab. Anim. Sci. 27: 700–702.Google Scholar
  63. Kuehl, T. J., and Dukelow, W. R., 1975a, Ovulation induction during the anovulatory season in Saimiri sciureus, J. Med. Primato4: 23–31.Google Scholar
  64. Kuehl, T. J., and Dukelow, W. R., 1975b, Fertilization in vitro of Saimiri sciureus follicular oocytes, J. Med. Primato4: 209–216.Google Scholar
  65. Kuehl, T. J., and Dukelow, W. R., 1978, The effect of a synthetic polypeptide, threonyl-prolylarginyl-lysine, on ovulation in the squirrel monkey (Saimiri sciureus) and hamster, J. Reprod. Fertil. 52: 25–28.PubMedCrossRefGoogle Scholar
  66. Kuehl, T. J., and Dukelow, W. R., 1979, Maturation and in vitro fertilization of follicular oocytes of the squirrel monkey (Saimiri sciureus), Biol. Reprod. 21: 545–556.CrossRefGoogle Scholar
  67. Kuehl, T. J., and Dukelow, W. R., 1982, Time relations of squirrel monkey (Saimiri sciureus) sperm capacitation and ovum maturation in an in vitro fertilization system, J. Reprod. Fertil. 64: 135–137.PubMedCrossRefGoogle Scholar
  68. Lang, C. M., 1967, The estrous cycle of the squirrel monkey (Saimiri sciureus), Lab. Anim. Care 17 (5): 442–451.Google Scholar
  69. Latta, J., Hopf, S., Ploog, D., 1969, Observations on mating behavior and sexual play in the squirrel monkey, Primates 8: 229–246.CrossRefGoogle Scholar
  70. Lin, T.-M., and Halbert, S. P., 1978, Immunological relationships of human and subhuman primate pregnancy-associated plasma proteins, Int. Arch. Allergy Appl. Immunol. 56: 207–223.PubMedCrossRefGoogle Scholar
  71. Lorenz, R., Anderson, C. O., and Mason, W. A., 1973, Notes on reproduction in captive squirrel monkeys (Saimiri sciureus), Folia Primato19: 286–292.CrossRefGoogle Scholar
  72. Luckett, W. P., 1974, Comparative development and evolution of the placenta in primates, in: Contributions to Primatology, Volume 3, Karger, Basel, pp. 142–234.Google Scholar
  73. McClure, H. M., and Chang, J., 1975, Ectopic pregnancy in a squirrel monkey, J. Am. Vet. Med. Assoc. 1975: 167–168.Google Scholar
  74. Mizoguchi, H., and Dukelow, W. R., 1981, Gradual fixation method for chromosomal studies of squirrel monkey oocytes after gonadotropin treatment, J. Med. Primato10: 180–186.Google Scholar
  75. Nathan, T. S., Rosenblum, L. A., Limson, G., and Nelson, J. H., 1966, Diagnosis of pregnancy in the squirrel monkey, Anat. Rec. 155: 531–536.Google Scholar
  76. Price, R. A., Anver, M. R., and Garcia, F. G., 1972, Simian neonatology I. Gestational maturity and extrauterine viability, Vet. Pathol. 9: 301–309.Google Scholar
  77. Rasmussen, K. M., Thenen, S.W., and Hayes, K. C., 1979, Folacin deficiency and requirement in the squirrel monkey (Saimiri sciureus), Am. J. Clin. Nutr. 32: 2508–2518.PubMedGoogle Scholar
  78. Rasmussen, K. M., Ausman, L. M., and Hayes, K. C., I980a, Vital statistics from a laboratory breeding colony of squirrel monkeys (Saimiri sciureus), Lab. Anim. Sci. 30: 99–106.Google Scholar
  79. Rasmussen, K. M., Thenen, S. W., and Hayes, K. C., 1980b, Effect of folic acid supplementation on pregnancy in the squirrel monkey (Saimiri sciureus), J. Med. Primato9: 169–184.Google Scholar
  80. Rawlins, R. G., 1983, Blastomere separation and culture techniques for hamster and squirrel monkey ova, Proc. Mich. Acad. Sci. p. 17.Google Scholar
  81. Rawson, J. M. R., and Dukelow, W. R., 1978, Effects of intrafollicular administration of gonadotropins in two species of nonhuman primates using laparoscopy, J. Med. Primato7: 223–227.Google Scholar
  82. Richter, C. P., 1976, Artificial seven-day cycles in spontaneous activity in wild rodents and squirrel monkeys, J. Comp. Physiol. Psycho(. 90: 572–582.CrossRefGoogle Scholar
  83. Rosenblum, L. A., 1968, Some aspects of female reproductive physiology in the squirrel monkey, in: The Squirrel Monkey ( L. A. Rosenblum and R. W. Cooper, eds.), pp. 147–170, Academic Press, New York.Google Scholar
  84. Rosenblum, L. A., Nathan, T., Nelson, J., and Kaufman, I. C., 1967, Vaginal cornification cycles in the squirrel monkey (Saimiri sciureus), Folia Primato!. 6: 83–91.CrossRefGoogle Scholar
  85. Setchell, K. D. R., Chua, K. S., and Himsworth, R. L., 1977, Urinary steroid excretion by the squirrel monkey (Saimiri sciureus), J. Endocrinol. 73: 365–375.PubMedCrossRefGoogle Scholar
  86. Srivastava, P. K., Cavazos, F., and Lucas, F. V., 1970a, Biology of reproduction in the squirrel monkey (Saimiri sciureus): I. The estrus cycle, Primates 11: 125–134.CrossRefGoogle Scholar
  87. Srivastava, P. K. Cavazos, F., and Lucas, F. V., 1970b, Biology of reproduction in the squirrel monkey (Saimiri sciureus): II. The ovary, Primates 11: 265–270.CrossRefGoogle Scholar
  88. Stolzenberg, S. J., Jones, D. C. L., Kaplan, J. N., Barth, R. A., Hodgen, G. D., and Madan, S. M., 1979, Studies with timed-pregnant squirrel monkeys (Saimiri sciureus), J. Med. Primato8: 29–38.Google Scholar
  89. Taub, D. M., 1980, Age at first pregnancy and reproductive outcome among colony-born squirrel monkeys (Saimiri sciureus, Brazilian), Folia Primato. 33: 262–272.CrossRefGoogle Scholar
  90. Taub, D. M., Adams, M. R., and Auerbach, K. G., 1978, Reproductive performance in a breeding colony of Brazilian squirrel monkeys (Saimiri sciureus), Lab. Anim. Sci. 28: 562–566.Google Scholar
  91. Travis, J. C., and Holmes, W. N., 1974, Some physiological and behavioral changes associated with oestrus and pregnancy in the squirrel monkey (Saimiri sciureus), J. Zool. Lond. 174: 41–66.CrossRefGoogle Scholar
  92. Tsuji, K., and Tatsumi, T., 1981, Some experiences of captive breeding of squirrel monkeys (Saimiri sciureus), Jpn. J. Med. Sci. Biol. 34: 259–261.PubMedGoogle Scholar
  93. Wilson, M. I., 1977, Characterization of the oestrous cycle and mating season of squirrel monkeys from copulatory behavior, J. Reprod. Fertil. 51: 57–63.PubMedCrossRefGoogle Scholar
  94. Wiswell, O. B., 1965, Gestation, parturition and maturation in the Saimiri sciureus (squirrel monkey), Excerpta Med. Int. Congr. Sera 99: E52.Google Scholar
  95. Wolf, R. C., O’Connor, R. F., and Robinson, J. A., 1977, Cyclic changes in plasma progestins and estrogens in squirrel monkeys, Biol. Reprod. 17: 228–231.CrossRefGoogle Scholar
  96. Wolf, R. H., Harrison, R. M., and Martin, T. W., 1975, A review of reproductive patterns in new world monkeys, Lab. Anim. Sci. 25: 814–821.Google Scholar

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© Springer Science+Business Media New York 1985

Authors and Affiliations

  • W. Richard Dukelow
    • 1
  1. 1.Endocrine Research CenterMichigan State UniversityEast LansingUSA

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