Cerebrospinal Fluid Proteins in Pathology

  • A. Lowenthal
  • D. Karcher

Abstract

Clinicians are currently showing increasing interest in the study of the CSF. This interest can be estimated from the great number of recent publications devoted to the subject.1 Human CSF proteins have been examined quantitatively and qualitatively. The quantitative examinations concern the determination of the total protein content, determinations of isolated, characterized proteins, or enzymatic determinations. Qualitative analysis is obtained in most cases by electrophoretic studies, often combined with immunologic assays. With these two approaches to the study of neurological disease, conclusions can be drawn that lead to diagnosis and to therapy as well. Many methodological applications, however, still need to be questioned. We shall discuss the problems that arise from the study of human CSF proteins in normal and pathological subjects in terms of (1) methodology and (2) known anomalies occurring in various neurological diseases.

Keywords

Myelin Basic Protein Bacterial Meningitis Nervous Tissue Total Protein Content Adenylate Kinase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • A. Lowenthal
    • 1
  • D. Karcher
    • 1
  1. 1.Laboratory of Neurochemistry, Born-Bunge FoundationUniversitaire Instelling AntwerpenAntwerpBelgium

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